ATI RN
ATI Pharmacology Proctored Exam 2019
1. A healthcare professional is preparing to administer Filgrastim for the first time to a client who has just undergone a bone marrow transplant. Which of the following interventions is appropriate?
- A. Administer subcutaneously in a large muscle mass to prevent injury.
- B. Ensure that the medication is kept at room temperature until just prior to administration.
- C. Invert vial gently to mix well before withdrawing dose.
- D. Discard vial after removing one dose of the medication.
Correct answer: D
Rationale: The correct intervention when preparing to administer Filgrastim is to discard the vial after removing one dose of the medication. This practice helps prevent contamination and ensures the medication's effectiveness. Reusing the vial can lead to contamination and compromise the sterility of the medication, putting the client at risk. Therefore, it is crucial to follow proper aseptic technique and discard the vial after withdrawing the prescribed dose.
2. A client has a new prescription for Propranolol. Which of the following findings should the healthcare provider identify as a contraindication to this medication?
- A. Asthma
- B. Diabetes mellitus
- C. Hypertension
- D. Glaucoma
Correct answer: A
Rationale: Propranolol is a non-selective beta-blocker that can cause bronchoconstriction, making it contraindicated for clients with asthma. Asthma is a contraindication for Propranolol due to the potential of worsening bronchoconstriction and causing respiratory distress in individuals with this condition. Diabetes mellitus, hypertension, and glaucoma are not contraindications for Propranolol.
3. A client has a Cerebrospinal fluid infection with gram-negative bacteria. Which of the following Cephalosporin antibiotics should be administered IV to treat this infection?
- A. Cefaclor
- B. Cefazolin
- C. Cefepime
- D. Cephalexin
Correct answer: C
Rationale: In treating a Cerebrospinal fluid infection caused by gram-negative bacteria, Cefepime, a fourth-generation cephalosporin, is the most suitable choice due to its enhanced efficacy against gram-negative organisms in such infections. Cefaclor (Choice A) is a second-generation cephalosporin more commonly used for respiratory tract infections. Cefazolin (Choice B) is a first-generation cephalosporin often used for skin and soft tissue infections. Cephalexin (Choice D) is a first-generation cephalosporin indicated for skin and urinary tract infections, but not the optimal choice for a Cerebrospinal fluid infection with gram-negative bacteria.
4. A client is being discharged with a new prescription for Clopidogrel. Which of the following instructions should the nurse include?
- A. Avoid taking aspirin while on this medication.
- B. Take this medication with food.
- C. Avoid eating foods high in potassium.
- D. Take this medication at bedtime.
Correct answer: A
Rationale: The correct instruction for a client prescribed Clopidogrel is to avoid taking aspirin while on this medication. Clopidogrel is an antiplatelet medication that can increase the risk of bleeding. Aspirin and other NSAIDs can potentiate the risk of bleeding, so they should be avoided while taking Clopidogrel to prevent adverse effects. Choices B, C, and D are incorrect because Clopidogrel does not need to be taken with food, there is no specific dietary restriction related to potassium, and the timing of administration (bedtime) is not a critical instruction for this medication.
5. Which of the following drugs is associated with Stevens-Johnson syndrome?
- A. Valproic acid
- B. Quinidine
- C. Isoniazid
- D. Ethosuximide
Correct answer: D
Rationale: Stevens-Johnson syndrome is a severe skin reaction that can be associated with Ethosuximide.
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