ATI RN
ATI Pharmacology
1. A healthcare professional is preparing to administer clindamycin 200 mg by intermittent IV bolus. The amount available is clindamycin injection 200 mg in 100 mL 0.9% sodium chloride (0.9% NaCl) to infuse over 30 min. The healthcare professional should set the IV pump to deliver how many mL/hr?
- A. 200 mL/hr
- B. 150 mL/hr
- C. 100 mL/hr
- D. 250 mL/hr
Correct answer: A
Rationale: To calculate the flow rate in mL/hr: (Volume in mL / Time in hours) = Flow rate in mL/hr. In this case, (100 mL / 0.5 hr) = 200 mL/hr. The correct calculation is: 100 mL (volume) / 0.5 hr (time) = 200 mL/hr. Therefore, the correct answer is 200 mL/hr. Choice B (150 mL/hr), C (100 mL/hr), and D (250 mL/hr) are incorrect as they do not match the calculated flow rate needed for the administration of clindamycin.
2. A client has a new prescription for Verapamil to control hypertension. Which of the following instructions should the nurse include?
- A. Increase the amount of dietary fiber in the diet.
- B. Drink grapefruit juice daily to increase vitamin C intake.
- C. Decrease the amount of calcium in the diet.
- D. Withhold food for 1 hr after taking the medication.
Correct answer: A
Rationale: Increasing dietary fiber intake is essential when taking Verapamil to prevent constipation, a common adverse effect of this medication. Verapamil is a calcium channel blocker used to treat hypertension, and dietary fiber helps maintain bowel regularity and prevent constipation that may occur as a side effect of the medication.
3. A client is taking Glipizide to treat Diabetes Mellitus. Which of the following laboratory tests should the nurse monitor to evaluate the effectiveness of this medication?
- A. Cholesterol level.
- B. Hematocrit.
- C. Blood glucose level.
- D. Calcium level.
Correct answer: C
Rationale: The correct answer is C: Blood glucose level. Monitoring the client's blood glucose level is crucial when taking Glipizide, a medication used to lower blood glucose levels in individuals with Diabetes Mellitus. By monitoring the blood glucose level, the nurse can evaluate the effectiveness of the medication in managing the client's condition. Choices A, B, and D are incorrect as they are not directly related to assessing the effectiveness of Glipizide in treating Diabetes Mellitus. Cholesterol level, hematocrit, and calcium level may be important for other aspects of the client's health but are not the primary indicators of Glipizide's effectiveness.
4. A client with schizophrenia is being taught strategies to cope with anticholinergic effects of Fluphenazine. Which of the following should the nurse suggest to the client to minimize anticholinergic effects?
- A. Take the medication in the morning to prevent insomnia.
- B. Chew sugarless gum to moisten the mouth.
- C. Use cooling measures to decrease fever.
- D. Take an antacid to relieve nausea.
Correct answer: B
Rationale: Chewing sugarless gum is an effective strategy to manage dry mouth, a common anticholinergic effect of Fluphenazine. By stimulating saliva production, sugarless gum helps to moisten the mouth and alleviate the discomfort associated with dryness. This intervention can improve the client's oral health and overall comfort while taking the medication. The other options are not directly related to alleviating anticholinergic effects. Taking the medication in the morning to prevent insomnia does not address anticholinergic effects specifically. Using cooling measures to decrease fever is not relevant to managing dry mouth caused by anticholinergic effects. Taking an antacid to relieve nausea is unrelated to managing dry mouth, which is the focus of anticholinergic effects.
5. A client is receiving vancomycin. Which of the following laboratory results should be monitored to evaluate the therapeutic effect of this medication?
- A. BUN
- B. Creatinine
- C. Hemoglobin
- D. White blood cell count
Correct answer: B
Rationale: Corrected Rationale: Creatinine levels should be monitored to evaluate vancomycin's effect on kidney function. Vancomycin can be nephrotoxic, so monitoring creatinine levels helps assess renal function and ensure that the medication is not causing harm to the kidneys. Monitoring BUN (choice A) is important for assessing kidney function but is not as specific as monitoring creatinine levels. Hemoglobin (choice C) and white blood cell count (choice D) are not directly related to evaluating the therapeutic effect of vancomycin.
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