ATI RN
ATI Pharmacology
1. When caring for a client receiving treatment with irinotecan, which of the following findings should the nurse monitor?
- A. Diarrhea
- B. Hypertension
- C. Ototoxicity
- D. Neutropenia
Correct answer: A
Rationale: The correct answer is diarrhea. Irinotecan commonly causes diarrhea as an adverse effect due to its impact on the gastrointestinal tract. Monitoring for diarrhea is essential to prevent dehydration and manage this side effect effectively. Choices B, C, and D are incorrect as hypertension, ototoxicity, and neutropenia are not commonly associated with irinotecan therapy.
2. A client informs the nurse that she has difficulty swallowing tablets and struggles with liquid or chewable medications due to taste. What medication should the nurse request a prescription for when preparing to administer Penicillin V to treat the client's streptococcal infection?
- A. Fosfomycin
- B. Amoxicillin
- C. Nafcillin
- D. Cefaclor
Correct answer: C
Rationale: Nafcillin is an appropriate alternative within the penicillin class for clients who have difficulty swallowing tablets or struggle with liquid or chewable medications. It is available for intramuscular (IM) or intravenous (IV) administration, offering options beyond oral formulations. Fosfomycin, Amoxicillin, and Cefaclor are not suitable alternatives for Penicillin V in this scenario as they belong to different classes of antibiotics and may not be as effective in treating streptococcal infections.
3. Medications classified as angiotensin II receptor agents typically end in?
- A. Sartan
- B. Ase
- C. Olol
- D. Pril
Correct answer: A
Rationale: Angiotensin II receptor agents belong to the drug class called angiotensin II receptor blockers (ARBs). The generic names of ARBs usually end in -sartan, helping to identify this specific class of medications. Therefore, medications that end in -sartan are likely to be angiotensin II receptor agents. Choices B, C, and D are incorrect because drugs ending in -ase (like streptokinase), -olol (like propranolol), and -pril (like lisinopril) typically belong to different drug classes with distinct mechanisms of action.
4. A client has a new prescription for Simvastatin. Which of the following client statements indicates an understanding of the teaching?
- A. I will take this medication at bedtime.
- B. I should avoid eating grapefruit while taking this medication.
- C. I will need to monitor my blood sugar closely while taking this medication.
- D. I will stop taking the medication if I develop muscle pain.
Correct answer: B
Rationale: The correct answer is B. Grapefruit can increase the levels of simvastatin in the blood, leading to an increased risk of serious side effects, including muscle pain or damage. Therefore, it is crucial for the client to avoid consuming grapefruit while taking this medication to prevent potential complications.
5. A healthcare professional is preparing to administer Spironolactone to a client. Which of the following laboratory results should the professional review before administering this medication?
- A. Serum potassium.
- B. Serum sodium.
- C. Serum chloride.
- D. Serum calcium.
Correct answer: A
Rationale: When administering Spironolactone, it is essential to monitor the client's serum potassium levels because Spironolactone is a potassium-sparing diuretic. Monitoring potassium levels helps to detect hyperkalemia, a potential adverse effect of the medication.
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