ATI RN
ATI Anatomy and Physiology
1. Which part of the nephron is closest to the collecting duct?
- A. Distal convoluted tubule (DCT)
- B. Bowman's Capsule
- C. Afferent Arteriole
- D. Proximal Convoluted Tubule (PCT)
Correct answer: A
Rationale: The correct answer is the Distal convoluted tubule (DCT). The DCT is the part of the nephron closest to the collecting duct, where the final adjustments to electrolyte and fluid balance are made. Bowman's Capsule is located at the beginning of the nephron, where filtration of blood occurs. The Afferent Arteriole brings blood to the glomerulus for filtration. The Proximal Convoluted Tubule (PCT) is situated after the Bowman's Capsule and is not the part closest to the collecting duct.
2. What causes wrinkled and sagging skin?
- A. Drinking too much water
- B. Heredity alone
- C. Loss of subcutaneous fat and reduced levels of elastin and collagen
- D. Excess subcutaneous fat
Correct answer: C
Rationale: Wrinkled and sagging skin is primarily caused by the loss of subcutaneous fat and reduced levels of elastin and collagen in the skin. Choice A is incorrect as drinking too much water does not lead to wrinkled and sagging skin. Choice B is incorrect because heredity alone does not cause this condition. Excess subcutaneous fat, as mentioned in Choice D, can contribute to a different skin appearance, such as puffiness, but not wrinkled and sagging skin.
3. An obstetrician tells a 42-year-old patient that she can have a healthy baby, but that she is of 'advanced maternal age.' The patient is so upset that she fails to listen to the rest of the doctor's advice, goes home in a huff, and immediately dyes her hair.
- A. the age of the sperm.
- B. the age of her eggs.
- C. her risk of developing diabetes.
- D. her cholesterol level, not her appearance.
Correct answer: B
Rationale: The correct answer is 'the age of her eggs.' As women age, the quality of their eggs decreases, leading to a higher risk of chromosomal abnormalities and infertility. This decline in egg quality is why advanced maternal age is associated with a higher risk of certain pregnancy complications. Choices A, C, and D are incorrect because the primary concern in this context is related to the age-related changes in a woman's eggs, not sperm, diabetes risk, or cholesterol levels.
4. Signs of aging at the cellular level are
- A. graying hair, waning strength, and wrinkles.
- B. unrepaired DNA and abnormal proteins.
- C. impaired cell division and the ability to break down and recycle worn cell parts.
- D. a fatty liver and clogged blood vessels.
Correct answer: C
Rationale: The correct answer is 'impaired cell division and the ability to break down and recycle worn cell parts.' Aging at the cellular level involves reduced efficiency in cell division and the breakdown/recycling of cellular components, leading to functional decline. Choices A, B, and D are incorrect because they involve external physical manifestations or organ-specific issues rather than cellular-level changes associated with aging.
5. Positive feedback mechanisms usually result in
- A. changes returning values away from a set point.
- B. stable conditions around a set point.
- C. unstable conditions.
- D. long-term changes.
Correct answer: C
Rationale: Positive feedback mechanisms usually result in unstable conditions. In a positive feedback loop, the output enhances or amplifies the changes that are occurring, leading to a deviation from the initial set point. Therefore, positive feedback does not bring values back towards the set point (Choice A). Choice B is incorrect because positive feedback does not promote stability around a set point. Choice D is also incorrect as positive feedback mechanisms typically do not lead to long-term changes; instead, they intensify the initial change, causing instability.
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