ATI RN
ATI Proctored Pharmacology Test
1. When administering Phenytoin, what should you monitor?
- A. Behavior
- B. Therapeutic blood levels
- C. For signs of Stevens-Johnson syndrome
- D. All of the above
Correct answer: D
Rationale: When administering Phenytoin, monitoring the patient's behavior is important to assess for any changes that may indicate adverse effects. Monitoring therapeutic blood levels helps ensure the medication is within the effective range and not causing toxicity. Additionally, being vigilant for signs of Stevens-Johnson syndrome, a severe skin reaction associated with Phenytoin use, is crucial for early detection and intervention. Therefore, monitoring behavior, therapeutic blood levels, and for signs of Stevens-Johnson syndrome are all essential when administering Phenytoin.
2. A client with Hodgkin's disease is receiving Cyclophosphamide IV. Which medication should be administered concurrently to prevent an adverse effect of Cyclophosphamide?
- A. Uroprotectant agent, such as mesna
- B. Opioid, such as morphine
- C. Loop diuretic, such as furosemide
- D. H1 receptor antagonist, such as diphenhydramine
Correct answer: A
Rationale: Mesna, an uroprotectant agent, is administered with nitrogen mustard chemotherapy drugs like Cyclophosphamide to prevent hemorrhagic cystitis, a common adverse effect. Mesna works by binding to and inactivating the toxic metabolites of Cyclophosphamide in the bladder, thereby reducing the risk of bladder toxicity.
3. A client has a new prescription for Calcitonin-salmon for Osteoporosis. Which of the following tests should the client expect before beginning this medication?
- A. Skin test for allergy to the medication
- B. ECG to rule out cardiac dysrhythmias
- C. Mantoux test to rule out exposure to tuberculosis
- D. Liver function tests to assess risk for medication toxicity
Correct answer: A
Rationale: Before initiating Calcitonin-salmon, a skin test for allergy to the medication may be performed to prevent anaphylactic reactions. Allergic reactions can occur due to sensitivities to the drug, particularly in individuals with fish allergies. Therefore, it is essential for healthcare providers to assess the client's potential allergic response to Calcitonin-salmon through a skin test. The other options are not relevant in this context. An ECG is not typically required before starting Calcitonin-salmon for Osteoporosis, nor is a Mantoux test or liver function tests.
4. A client with congestive heart failure taking digoxin refused breakfast and is complaining of nausea and weakness. Which action should the nurse take first?
- A. Check the client's vital signs.
- B. Request a consult with a dietitian.
- C. Suggest that the client rests before eating the meal.
- D. Request an order for an antiemetic.
Correct answer: A
Rationale: The nurse should check the client's vital signs first because nausea and weakness can be signs of digoxin toxicity. Vital signs can provide immediate information on the client's condition and help guide further interventions. Monitoring vital signs will allow the nurse to assess for bradycardia, a common sign of digoxin toxicity. Requesting a dietitian consult (choice B) may be necessary but addressing the immediate concern of toxicity is the priority. Suggesting rest before eating (choice C) may not address the underlying issue of digoxin toxicity. Requesting an antiemetic (choice D) can be considered later but is not the initial action needed in this situation.
5. A client with chronic myeloid leukemia is receiving hydroxyurea. Which of the following findings should the nurse monitor?
- A. Hyperkalemia
- B. Hypertension
- C. Neutropenia
- D. Tinnitus
Correct answer: C
Rationale: The nurse should monitor the client for neutropenia when receiving hydroxyurea, as it is a common adverse effect caused by bone marrow suppression. Neutropenia increases the risk of infections, making it crucial for the nurse to closely monitor the client's white blood cell count.
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