ATI RN
ATI Pharmacology Test Bank
1. What is the therapeutic use of Phenytoin?
- A. Replacement in hypothyroidism to restore normal hormonal balance
- B. Diminished accumulation of acid in the gastric lumen with lessened gastroesophageal reflux
- C. Diminished seizure activity, termination of ventricular arrhythmias
- D. Prevention of thrombus formation, prevention of extension of existing thrombi
Correct answer: C
Rationale: Phenytoin is primarily used to diminish seizure activity and is effective in terminating ventricular arrhythmias. It works by stabilizing neuronal membranes, reducing repetitive neuronal firing, and limiting the spread of seizure activity in the brain. While phenytoin does not have a direct role in preventing thrombus formation or extending existing thrombi, it is crucial in managing seizures and certain arrhythmias.
2. A client has a new prescription for Nitroglycerin to treat angina. Which of the following instructions should be included?
- A. Take this medication only when experiencing chest pain.
- B. Store the medication in a cool, dry place.
- C. Apply the patch to a different site each time.
- D. Do not cut the patch regardless of your blood pressure.
Correct answer: C
Rationale: When using Nitroglycerin patches to treat angina, it is crucial to apply the patch to a different site each time. This practice helps prevent skin irritation and ensures proper absorption of the medication, optimizing its effectiveness in managing angina symptoms.
3. A healthcare provider is reviewing the health history of a client who is starting therapy with tamoxifen. The healthcare provider should recognize that tamoxifen is contraindicated in which of the following clients?
- A. A client with a history of deep-vein thrombosis
- B. A client with a history of migraine headaches
- C. A client with a history of hypertension
- D. A client with a history of anemia
Correct answer: A
Rationale: Tamoxifen is contraindicated in clients with a history of thromboembolic events, such as deep-vein thrombosis, due to the increased risk of blood clots forming and leading to serious complications like pulmonary embolism. Clients with a history of deep-vein thrombosis are at a higher risk of recurrent thromboembolic events when taking tamoxifen, making it unsafe for such individuals. Choices B, C, and D are not contraindications for tamoxifen therapy, as migraine headaches, hypertension, and anemia do not directly interact with tamoxifen's mechanism of action or pose significant risks when used together.
4. A client has a new prescription for Beclomethasone. Which of the following instructions should the nurse include?
- A. Rinse your mouth after each use of this medication.
- B. Limit fluid intake while taking this medication.
- C. Increase your intake of vitamin B12 while taking this medication.
- D. You can take the medication as needed.
Correct answer: A
Rationale: The correct instruction the nurse should provide is to rinse the mouth after each use of Beclomethasone. This practice helps reduce the risk of developing oral fungal infections associated with inhaled corticosteroids. Choice B is incorrect because there is no need to limit fluid intake while taking this medication. Choice C is incorrect as there is no specific indication to increase vitamin B12 intake with Beclomethasone. Choice D is incorrect as Beclomethasone should be used according to the prescribed schedule, not as needed.
5. What should a patient avoid while taking Angiotensin-converting enzymes?
- A. Salt substitutes
- B. Foods high in potassium
- C. Foods high in sodium
- D. All of the above
Correct answer: A
Rationale: Patients taking Angiotensin-converting enzyme (ACE) inhibitors should avoid salt substitutes because they can contain potassium chloride, which may lead to hyperkalemia. It is important to restrict potassium-rich foods while on ACE inhibitors, but the primary concern with salt substitutes is their potassium content.
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