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MSN 570 Advanced Pathophysiology Final 2024
1. In chronic obstructive pulmonary disease, the inflammatory response predominantly involves:
- A. eosinophils
- B. neutrophils
- C. monocytes
- D. cells
Correct answer: B
Rationale: In chronic obstructive pulmonary disease, the inflammatory response predominantly involves neutrophils. Neutrophils play a key role in COPD due to their involvement in initiating and sustaining the inflammatory process. Eosinophils are more commonly associated with asthma rather than COPD. Monocytes are less involved in the inflammatory response in COPD compared to neutrophils. The choice 'cells' is too broad and vague to be a specific answer in this context.
2. A woman suffers from amenorrhea. Which of the following medications will most likely be prescribed?
- A. Testosterone
- B. Follicle-stimulating hormone
- C. Estrogen
- D. Lactate
Correct answer: C
Rationale: Estrogen is the correct answer. Amenorrhea, the absence of menstruation, is often due to hormonal imbalances. Estrogen plays a crucial role in regulating the menstrual cycle. Prescribing estrogen can help address these hormonal imbalances and restore menstrual cycles. Testosterone (Choice A) is not typically prescribed for amenorrhea in women as it can further disrupt hormonal balance. Follicle-stimulating hormone (Choice B) is involved in stimulating ovulation and follicle development, not the primary treatment for amenorrhea. Lactate (Choice D) is not a medication used to treat amenorrhea.
3. In emphysema, what features result in impaired oxygenation?
- A. The bronchioles are inflamed and filled with mucus
- B. The alveoli have lost surfactant and collapse
- C. Enlarged, permanently inflated alveoli
- D. The accumulation of purulent fluid in the bronchioles
Correct answer: C
Rationale: The correct answer is C. In emphysema, impaired oxygenation results from enlarged and permanently inflated alveoli, leading to reduced surface area for gas exchange. Choices A, B, and D are incorrect. In emphysema, bronchioles are not typically filled with mucus, alveoli losing surfactant and collapsing is more characteristic of conditions like atelectasis, and purulent fluid accumulation in the bronchioles is commonly seen in conditions like pneumonia, not emphysema.
4. A 57-year-old male presents to his primary care provider with a red face, hands, feet, ears, headache, and drowsiness. A blood smear reveals an increased number of erythrocytes, indicating:
- A. Leukemia
- B. Sideroblastic anemia
- C. Hemosiderosis
- D. Polycythemia vera
Correct answer: D
Rationale: In this case, the symptoms of a red face, hands, feet, ears, headache, and drowsiness along with an increased number of erythrocytes in the blood smear are indicative of polycythemia vera. This condition is characterized by the overproduction of red blood cells, leading to symptoms related to increased blood volume and viscosity. Leukemia (Choice A) is a cancer of the blood and bone marrow, but the presentation described here is more suggestive of polycythemia vera. Sideroblastic anemia (Choice B) is characterized by abnormal iron deposits in erythroblasts, not an increased number of erythrocytes. Hemosiderosis (Choice C) refers to abnormal accumulation of iron in the body, not an increase in red blood cells as seen in polycythemia vera.
5. Which of the following describes the condition in the body of clients experiencing hypovolemia?
- A. Increased urine retention
- B. Insufficient circulating blood volume
- C. Bounding peripheral pulses
- D. Crackles auscultated in the lungs
Correct answer: B
Rationale: The correct answer is B: Insufficient circulating blood volume. Hypovolemia is a condition characterized by a decrease in the volume of blood plasma. This reduction in circulating blood volume can lead to inadequate perfusion of tissues and organs, potentially resulting in shock if left untreated. Choices A, C, and D are incorrect because increased urine retention, bounding peripheral pulses, and crackles auscultated in the lungs are not typical manifestations of hypovolemia.
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