ATI RN
ATI Pathophysiology Final Exam
1. What are direct effects of antibodies? (Select ONE that does not apply):
- A. Neutralization
- B. Agglutination
- C. Precipitation
- D. Phagocytosis
Correct answer: D
Rationale: The direct effects of antibodies include neutralization, agglutination, and precipitation. Antibodies neutralize pathogens by binding to them and preventing their harmful effects. Agglutination involves the clumping together of pathogens, making it easier for phagocytes to engulf them. Precipitation refers to the process where antibodies bind to soluble antigens, forming large complexes that are easily removed from the body. Phagocytosis, on the other hand, is an indirect effect of antibodies where phagocytes engulf and destroy pathogens opsonized by antibodies, not a direct effect.
2. What property is found in clients with metastatic cancer?
- A. Tumors that are well encapsulated
- B. Tumors with slow, stable growth
- C. Cells that are genetically stable
- D. Cells invading local tissue and overrunning neighboring cells
Correct answer: D
Rationale: Metastatic cancer is characterized by cells that invade local tissue and overrun neighboring cells. Therefore, the correct answer is D. Choices A, B, and C are incorrect because metastatic cancer is associated with aggressive behavior where cells invade and spread to other parts of the body, rather than being well encapsulated, growing slowly, or being genetically stable.
3. A nursing student is learning about the effects of bactericidal agents. How does rifampin (Rifadin) achieve a therapeutic action against both intracellular and extracellular tuberculosis organisms?
- A. It is metabolized in the liver.
- B. It binds to acetylcholine.
- C. It inhibits synthesis of RNA.
- D. It causes phagocytosis.
Correct answer: C
Rationale: Rifampin (Rifadin) achieves a therapeutic action against both intracellular and extracellular tuberculosis organisms by inhibiting the synthesis of RNA. This action interferes with bacterial RNA synthesis, leading to the suppression of protein synthesis in the bacteria, ultimately causing their death. Option A is incorrect because rifampin is primarily metabolized in the liver, but this is not how it exerts its bactericidal effects. Option B is incorrect as rifampin does not bind to acetylcholine. Option D is also incorrect as rifampin does not cause phagocytosis.
4. A student is feeling inside her backpack to find her mobile phone. There are a number of other items in the bag other than the phone. The nurse knows that which term best describes one's ability to sense the shape and size of an object in the absence of visualization?
- A. Stereognosis
- B. Graphesthesia
- C. Proprioception
- D. Kinesthesia
Correct answer: A
Rationale: Stereognosis is the correct answer. It refers to the ability to recognize objects by touch, specifically determining their shape and size without relying on visual cues. Graphesthesia, on the other hand, is the ability to recognize symbols or numbers traced on the skin. Proprioception involves the awareness of body position and movement. Kinesthesia relates to the perception of body movement.
5. When the maternal immune system becomes sensitized against antigens expressed by the fetus, what type of immune reaction occurs?
- A. Autoimmune
- B. Anaphylaxis
- C. Alloimmune
- D. Allergic
Correct answer: C
Rationale: When the maternal immune system becomes sensitized against antigens expressed by the fetus, an alloimmune reaction occurs. In this situation, the mother's immune system recognizes the fetus as foreign due to differences in antigens, leading to an immune response against the fetus. Choice A, 'Autoimmune,' is incorrect because it refers to the immune system mistakenly attacking the body's own cells and tissues. Choice B, 'Anaphylaxis,' is not the correct answer as it is a severe allergic reaction that can be life-threatening. Choice D, 'Allergic,' is also incorrect as it refers to an immune response triggered by allergens, not antigens expressed by the fetus.
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