ATI RN
ATI Pathophysiology Exam 2
1. When discussing the risks associated with hormone replacement therapy (HRT) with a patient who has a history of coronary artery disease, what should the nurse emphasize?
- A. HRT may increase the risk of cardiovascular events such as heart attack and stroke.
- B. HRT may increase the risk of osteoporosis.
- C. HRT may decrease the risk of venous thromboembolism.
- D. HRT may increase the risk of breast cancer.
Correct answer: A
Rationale: The correct answer is A. Hormone replacement therapy (HRT) is associated with an increased risk of cardiovascular events, such as heart attack and stroke, especially in patients with a history of coronary artery disease. Choice B is incorrect because HRT is actually known to decrease the risk of osteoporosis. Choice C is incorrect as HRT is associated with an increased risk of venous thromboembolism. Choice D is also incorrect as HRT may slightly increase the risk of breast cancer.
2. A client with a diagnosis of depression has been prescribed a medication that ultimately increases the levels of the neurotransmitter serotonin between neurons. Which process will accompany the actions of the neurotransmitter in a chemical synapse?
- A. Two-way communication between neurons is permitted, in contrast to the one-way communication in electrical synapses.
- B. Communication between a neuron and the single neuron it is connected with will be facilitated.
- C. The neurotransmitter will cross gap junctions more readily.
- D. More neurotransmitters will cross the synaptic cleft and bond with postsynaptic receptors.
Correct answer: D
Rationale: When serotonin levels increase, more neurotransmitters will cross the synaptic cleft and bind with postsynaptic receptors, facilitating enhanced communication. Option A is incorrect because chemical synapses, unlike electrical synapses, are unidirectional. Option B is incorrect because neurotransmitters impact communication with multiple neurons, not just a single connected neuron. Option C is incorrect because neurotransmitters cross the synaptic cleft, not gap junctions.
3. A male patient is receiving testosterone therapy for hypogonadism. What adverse effect should the nurse be most concerned about?
- A. Increased risk of breast cancer
- B. Increased risk of liver dysfunction
- C. Increased risk of cardiovascular events
- D. Increased risk of prostate cancer
Correct answer: C
Rationale: The correct answer is C: Increased risk of cardiovascular events. Cardiovascular events such as stroke and myocardial infarction are the most concerning adverse effects of testosterone therapy, especially in older patients. Choice A, increased risk of breast cancer, is not a common adverse effect of testosterone therapy in males. Choice B, increased risk of liver dysfunction, is a potential adverse effect but is not the most concerning. Choice D, increased risk of prostate cancer, is a consideration in patients with a history of prostate cancer or those with prostate carcinoma, not typically in patients receiving testosterone therapy for hypogonadism.
4. Which of the following is a characteristic of disseminated intravascular coagulation (DIC)?
- A. Simultaneous stroke and heart attack
- B. Simultaneous clotting and bleeding
- C. Simultaneous clotting and insulin release
- D. Simultaneous bleeding and vomiting
Correct answer: B
Rationale: Disseminated intravascular coagulation (DIC) is characterized by simultaneous clotting and bleeding throughout the body. This imbalance in the body's clotting system leads to the formation of blood clots in small blood vessels, which can consume clotting factors and platelets, ultimately leading to excessive bleeding. Choices A, C, and D are incorrect because they do not describe the characteristic feature of DIC, which involves both clotting and bleeding.
5. What are the signs of thyroid crisis resulting from Graves' disease?
- A. Constipation with gastric distension.
- B. Bradycardia and bradypnea.
- C. Hyperthermia and tachycardia.
- D. Constipation and lethargy.
Correct answer: C
Rationale: In a thyroid crisis resulting from Graves' disease, the patient typically experiences symptoms such as hyperthermia (elevated body temperature) and tachycardia (rapid heart rate). These symptoms are indicative of the hypermetabolic state seen in thyroid storm. Choices A and D are incorrect as constipation and lethargy are not typical signs of a thyroid crisis; instead, patients with hyperthyroidism often experience diarrhea and agitation. Choice B is incorrect because bradycardia (slow heart rate) and bradypnea (slow breathing rate) are more commonly associated with hypothyroidism rather than a thyroid crisis in Graves' disease.
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