ATI RN
WGU Pathophysiology Final Exam
1. A patient is prescribed tadalafil (Cialis) for erectile dysfunction. What critical contraindication should the nurse discuss with the patient?
- A. Use of nitrates
- B. Use of antihypertensive medications
- C. History of hypertension
- D. History of peptic ulcer disease
Correct answer: A
Rationale: The correct answer is A: Use of nitrates. Tadalafil (Cialis) is contraindicated in patients taking nitrates due to the risk of severe hypotension. Nitrates potentiate the hypotensive effects of tadalafil, leading to a potentially life-threatening drop in blood pressure. Choices B, C, and D are incorrect because antihypertensive medications, history of hypertension, and history of peptic ulcer disease are not critical contraindications for tadalafil use. While caution may be needed in patients with certain conditions, the highest priority is addressing the interaction with nitrates.
2. A 30-year-old has poorly controlled asthma and is taking prednisone 10 mg by mouth once a day. He has been on this regimen for 6 weeks. Abrupt withdrawal or discontinuation of this medication can cause:
- A. adrenal crisis
- B. hypercortisolism
- C. ACTH stimulation
- D. thyroid crisis
Correct answer: A
Rationale: Abrupt withdrawal or discontinuation of prednisone, a corticosteroid, can lead to adrenal crisis. This occurs due to the suppression of the adrenal glands' natural cortisol production caused by prolonged exogenous steroid administration. Adrenal crisis presents with symptoms such as weakness, fatigue, abdominal pain, and hypotension. Hypercortisolism (Cushing syndrome) results from chronic excessive exposure to cortisol, not abrupt withdrawal. ACTH stimulation would be expected in response to low cortisol levels, not as a direct consequence of prednisone withdrawal. Thyroid crisis (thyroid storm) is associated with severe hyperthyroidism and is not directly related to corticosteroid withdrawal.
3. The nurse is closely following a patient who began treatment with testosterone several months earlier. When assessing the patient for potential adverse effects of treatment, the nurse should prioritize which of the following assessments?
- A. Skin inspection for developing lesions
- B. Lung function testing
- C. Assessment of serum calcium levels
- D. Assessment of arterial blood gases
Correct answer: C
Rationale: In patients receiving testosterone therapy, the nurse should prioritize assessing serum calcium levels. Testosterone therapy can lead to hypercalcemia, making the evaluation of serum calcium levels crucial. Skin inspection for developing lesions, lung function testing, and arterial blood gas assessment are not the priority assessments for potential adverse effects of testosterone therapy. Skin inspection may be relevant for dermatological side effects, lung function testing and arterial blood gas assessment are not directly related to the common side effects of testosterone therapy.
4. Which of the following outcome criteria is appropriate for a client with dementia?
- A. The client will return to an established schedule for activities of daily living.
- B. The client will learn new coping mechanisms to handle anxiety.
- C. The client will seek out resources in the community for support.
- D. The client will follow an established schedule for activities of daily living.
Correct answer: D
Rationale: The correct answer is D. For clients with dementia, following an established schedule for activities of daily living is appropriate as it helps maintain routine and structure, which can be beneficial for their condition. Choice A has been rephrased to align better with the context of dementia care. Choice A is incorrect as expecting a return to a previous level of self-functioning may not be realistic for clients with dementia. Choice B is not the most appropriate outcome criteria as handling anxiety, while important, may not be the primary focus when working with clients with dementia. Choice C, seeking out resources in the community for support, is also important but may not be as directly related to the day-to-day care and management of activities for a client with dementia.
5. When starting on oral contraceptives, what should the nurse emphasize about the potential interactions with other medications?
- A. Oral contraceptives can be less effective when taken with certain antibiotics.
- B. Oral contraceptives are less effective when taken with food.
- C. Oral contraceptives are effective immediately after starting.
- D. Oral contraceptives have no interactions with other medications.
Correct answer: A
Rationale: The correct answer is A. Oral contraceptives can be less effective when taken with certain antibiotics, so patients should be informed about the potential need for additional contraception. Choice B is incorrect because taking oral contraceptives with food does not affect their effectiveness. Choice C is incorrect because oral contraceptives may take some time to become fully effective. Choice D is incorrect because oral contraceptives can interact with other medications, especially certain antibiotics, affecting their efficacy.
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