ATI RN
ATI Pharmacology Quizlet
1. A healthcare professional is reviewing the medication administration record for a client who is receiving transdermal Fentanyl for severe pain. Which of the following medications should the healthcare professional expect to cause an adverse effect when administered concurrently with Fentanyl?
- A. Ampicillin
- B. Diazepam
- C. Furosemide
- D. Prednisone
Correct answer: B
Rationale: Diazepam, a CNS depressant, can lead to severe sedation when administered concurrently with an opioid like Fentanyl due to their additive central nervous system depressant effects. This interaction can potentiate respiratory depression and other CNS effects, increasing the risk of adverse outcomes.
2. A client has a new prescription for Folic Acid. Which of the following client statements indicates an understanding of the teaching?
- A. I will take this medication with food.
- B. I need to monitor for skin rash while taking this medication.
- C. I need to increase my intake of green, leafy vegetables.
- D. I will stop taking this medication if I feel nauseous.
Correct answer: C
Rationale: The correct answer is C. Folic acid is naturally found in green, leafy vegetables such as spinach and broccoli. Increasing the intake of these vegetables can supplement the prescribed folic acid and help maintain adequate levels in the body. It is essential to understand that dietary sources of folic acid can complement the medication and support overall health. Choices A, B, and D are incorrect because taking folic acid with food, monitoring for skin rash, or stopping the medication if feeling nauseous do not directly relate to enhancing the therapeutic effects of folic acid through dietary intake.
3. A client has a new prescription for Clopidogrel. Which of the following instructions should the nurse include?
- A. Avoid taking aspirin while on this medication.
- B. Take this medication with food.
- C. Avoid eating foods high in potassium.
- D. Take this medication at bedtime.
Correct answer: A
Rationale: The correct answer is to instruct the client to avoid taking aspirin while on Clopidogrel. Clopidogrel is an antiplatelet medication that can increase the risk of bleeding. Aspirin and other NSAIDs can further potentiate this risk, so they should be avoided while taking Clopidogrel to reduce the chance of bleeding complications. Choices B, C, and D are incorrect. There is no specific instruction to take Clopidogrel with food or at bedtime. Avoiding foods high in potassium is not directly related to Clopidogrel use.
4. When a client is receiving treatment with methotrexate, which supplement should the nurse instruct the client to take?
- A. Folic acid
- B. Vitamin D
- C. Calcium
- D. Iron
Correct answer: A
Rationale: Folic acid supplementation is crucial for clients undergoing methotrexate treatment because methotrexate functions as a folic acid antagonist. By supplementing with folic acid, the risk of methotrexate toxicity can be minimized, improving the treatment's effectiveness and safety. Vitamin D, calcium, and iron are not specifically recommended in conjunction with methotrexate therapy and may not provide the same protective benefits as folic acid.
5. A provider prescribes phenobarbital for a client who has a seizure disorder. The medication has a long half-life of 4 days. How many times per day should the nurse expect to administer this medication?
- A. One
- B. Two
- C. Three
- D. Four
Correct answer: A
Rationale: Phenobarbital has a long half-life of 4 days, meaning it remains at therapeutic levels in the body for an extended period. Due to this prolonged duration of action, the nurse should expect to administer phenobarbital once a day to maintain therapeutic levels and effectiveness. Administering it more than once a day would lead to unnecessary dosing and potential adverse effects as the medication remains active in the body for an extended period.
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