ATI RN
ATI Pharmacology Test Bank
1. A client has a new prescription for Simvastatin. Which of the following client statements indicates an understanding of the teaching?
- A. I will take this medication at bedtime.
- B. I should avoid eating grapefruit while taking this medication.
- C. I will need to monitor my blood sugar closely while taking this medication.
- D. I will stop taking the medication if I develop muscle pain.
Correct answer: B
Rationale: The correct answer is B. Grapefruit can increase the levels of simvastatin in the blood, leading to an increased risk of serious side effects, including muscle pain or damage. Therefore, it is crucial for the client to avoid consuming grapefruit while taking this medication to prevent potential complications.
2. What is the therapeutic use of Phenytoin?
- A. Replacement in hypothyroidism to restore normal hormonal balance
- B. Diminished accumulation of acid in the gastric lumen with lessened gastroesophageal reflux
- C. Diminished seizure activity, termination of ventricular arrhythmias
- D. Prevention of thrombus formation, prevention of extension of existing thrombi
Correct answer: C
Rationale: Phenytoin is primarily used to diminish seizure activity and is effective in terminating ventricular arrhythmias. It works by stabilizing neuronal membranes, reducing repetitive neuronal firing, and limiting the spread of seizure activity in the brain. While phenytoin does not have a direct role in preventing thrombus formation or extending existing thrombi, it is crucial in managing seizures and certain arrhythmias.
3. A client has a new prescription for Zolpidem. Which of the following instructions should the nurse include?
- A. Notify the provider if you plan to become pregnant.
- B. Take the medication 1 hour before planning to go to sleep.
- C. Allow at least 6 hours for sleep when taking zolpidem.
- D. Do not take zolpidem with a bedtime snack.
Correct answer: A
Rationale: Zolpidem is classified as Pregnancy Risk Category C. It is important for the client to inform the provider if they plan to become pregnant because the medication may need to be adjusted or changed to ensure the safety of the fetus. This communication allows for appropriate monitoring and adjustments to be made to the treatment plan. Choice B is incorrect because zolpidem should be taken just before going to bed, not specifically 1 hour before. Choice C is incorrect as zolpidem is a short-acting medication, and it does not require a full 6 hours for sleep. Choice D is incorrect because zolpidem can be taken with or without food, so taking it with a bedtime snack is not contraindicated.
4. A healthcare provider is assessing a client who is taking levothyroxine. The healthcare provider should recognize that which of the following findings is a manifestation of levothyroxine overdose?
- A. Insomnia
- B. Constipation
- C. Drowsiness
- D. Hypoactive deep-tendon reflexes
Correct answer: A
Rationale: Insomnia is a common symptom of levothyroxine overdose due to excessive stimulation of the central nervous system. Levothyroxine is a thyroid hormone replacement medication, and an overdose can lead to hyperthyroidism symptoms, including insomnia. Constipation and drowsiness are not typically associated with levothyroxine overdose. Hypoactive deep-tendon reflexes are more indicative of hypothyroidism rather than an overdose of levothyroxine.
5. A client has a new prescription for Propranolol. Which of the following findings should the healthcare provider identify as a contraindication to this medication?
- A. Asthma
- B. Diabetes mellitus
- C. Hypertension
- D. Glaucoma
Correct answer: A
Rationale: Propranolol is a non-selective beta-blocker that can cause bronchoconstriction, making it contraindicated for clients with asthma. Asthma is a contraindication for Propranolol due to the potential of worsening bronchoconstriction and causing respiratory distress in individuals with this condition. Diabetes mellitus, hypertension, and glaucoma are not contraindications for Propranolol.
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