a nurse is caring for a client who has a prescription for gentamicin for the treatment of an infection the nurse should recognize that which of the fo

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ATI Pharmacology

1. A client is prescribed gentamicin for an infection. Which finding indicates a potential adverse reaction to the medication?

A. Blood pressure 160/90 mm Hg
B. Presence of red blood cells in the urine
C. Urine output of 35 mL/hr
D. Respiratory rate of 22/min

Correct answer: B

Rationale: The presence of red blood cells in the urine is a significant finding that can indicate nephrotoxicity, a potential adverse effect of gentamicin. Nephrotoxicity can lead to kidney damage, and monitoring for this adverse reaction is crucial during gentamicin therapy. Elevated blood pressure (Choice A) is not typically associated with gentamicin adverse reactions. Decreased urine output (Choice C) may suggest kidney impairment but is not as specific as the presence of red blood cells in the urine. Respiratory rate (Choice D) is not directly related to potential adverse reactions to gentamicin.

2. A nurse is teaching a client who has a new prescription for Prednisone. Which of the following instructions should the nurse include?

A. Increase your intake of vitamin
B. Take this medication on an empty stomach.
C. Avoid drinking grapefruit juice.
D. Take this medication every other day.

Correct answer: A

Rationale: Prednisone can lead to bone loss, so clients should increase their intake of vitamin D and calcium to help maintain bone health.

3. What are the actions of the drug metformin?

A. Decreases hepatic glucose production and intestinal glucose absorption
B. Increases sensitivity to insulin
C. Short-term sedation
D. Both A and B

Correct answer: D

Rationale: Metformin has dual actions by decreasing hepatic glucose production and intestinal glucose absorption, which helps in reducing blood glucose levels. Additionally, it increases sensitivity to insulin, aiding in its proper utilization within the body. Choice A is correct as metformin acts by decreasing hepatic glucose production and intestinal glucose absorption. Choice B is also correct as metformin increases sensitivity to insulin. Choice C, short-term sedation, is incorrect as metformin is not known for causing sedation. Therefore, the correct answer is D because metformin performs both of these actions.

4. When starting amitriptyline, a client should be instructed to monitor for which of the following adverse effects?

A. Diarrhea
B. Urinary retention
C. Bradycardia
D. Dry cough

Correct answer: B

Rationale: When a client starts taking amitriptyline, an important adverse effect to monitor for is urinary retention. Amitriptyline is a tricyclic antidepressant that can cause anticholinergic effects, including urinary retention. It is crucial to educate the client on recognizing and reporting this adverse effect to their healthcare provider. Diarrhea is not a common adverse effect of amitriptyline and is more associated with other medications. Bradycardia is a possible adverse effect of amitriptyline, but urinary retention is a more common and significant concern. Dry cough is not a typical adverse effect of amitriptyline.

5. What is a severe adverse effect of iron supplementation?

A. Seizures
B. Dry mouth
C. Edema
D. Serotonin syndrome

Correct answer: A

Rationale: A severe adverse effect of iron supplementation is seizures. Iron toxicity can lead to symptoms such as abdominal pain, vomiting, bloody diarrhea, lethargy, and in severe cases, seizures. It is important for individuals taking iron supplements to follow recommended dosages to prevent adverse effects.