a 10 year old male presents to his primary care provider reporting wheezing and difficulty breathing history reveals that both of the childs parents s

ATI RN

ATI Pathophysiology

1. A 10-year-old male presents to his primary care provider reporting wheezing and difficulty breathing. History reveals that both of the child's parents suffer from allergies. Which of the following terms would be used to classify the child?

A. Desensitized
B. Atopic
C. Hyperactive
D. Autoimmune

Correct answer: B

Rationale: In this case, the correct term to classify the child is 'Atopic.' Atopic individuals have a genetic predisposition to developing allergic conditions, as seen in this patient with a family history of allergies. 'Desensitized' refers to reduced sensitivity to an allergen, which is not the case here. 'Hyperactive' relates to an exaggerated response, and 'Autoimmune' involves the immune system attacking its own cells, neither of which accurately describes the child's classification based on the provided history.

2. A patient with a history of venous thromboembolism is prescribed hormone replacement therapy (HRT). What should the nurse emphasize about the risks associated with this therapy?

A. HRT is associated with an increased risk of venous thromboembolism, so patients should be educated about the signs and symptoms of blood clots.
B. HRT may improve mood and energy levels, but it also increases the risk of osteoporosis.
C. HRT can decrease the risk of fractures, but it also increases the risk of developing diabetes.
D. HRT may increase the risk of breast cancer, so regular mammograms are essential.

Correct answer: A

Rationale: HRT is associated with an increased risk of venous thromboembolism, so patients should be educated about the signs and symptoms of blood clots and advised to seek immediate medical attention if they occur.

3. A patient who is undergoing treatment for cytomegalovirus received his first dose of IV ganciclovir 3 days ago. When reviewing this patient's most recent blood work, what abnormality should the nurse most likely attribute to the use of this drug?

A. Hemoglobin 17 g/dL (high normal)
B. INR 3.8 (high)
C. Platelet count 118,000/mm3 (low)
D. Leukocytes 11,900/mm3 (high)

Correct answer: C

Rationale: The correct answer is C: Platelet count 118,000/mm3 (low). Ganciclovir, used to treat cytomegalovirus, is known to cause bone marrow suppression, leading to decreased platelet count (thrombocytopenia). This condition can increase the risk of bleeding. Choices A, B, and D are not typically associated with ganciclovir therapy. High hemoglobin levels (choice A) are not commonly seen with ganciclovir treatment. INR elevation (choice B) is associated with coagulation abnormalities, which are not a typical side effect of ganciclovir. Elevated leukocyte count (choice D) is not a common consequence of ganciclovir use.

4. Women who have breast cancer due to a BRCA1 gene mutation are usually:

A. positive for human epidermal growth factor receptor 1 and 2.
B. negative for estrogen receptor.
C. positive for estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2.
D. negative for estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2.

Correct answer: D

Rationale: Women with breast cancer due to a BRCA1 gene mutation commonly have a triple-negative breast cancer subtype, which means they are negative for estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 (HER2). This subtype tends to be more aggressive and harder to treat. Choice A is incorrect as they are typically negative for HER2. Choice B is incorrect because they are usually negative for estrogen receptor. Choice C is incorrect as they are usually negative for progesterone receptor and HER2.

5. What common symptom should be assessed in individuals with immunodeficiency?

A. Anemia
B. Recurrent infections
C. Hypersensitivity
D. Autoantibody production

Correct answer: B

Rationale: Recurrent infections are a hallmark symptom of immunodeficiency. Individuals with impaired immune systems are more susceptible to recurrent infections due to their compromised ability to fight off pathogens. Anemia (Choice A) is not a direct symptom of immunodeficiency but can be a consequence of chronic diseases. Hypersensitivity (Choice C) refers to exaggerated immune responses rather than impaired immune function. Autoantibody production (Choice D) is not typically a primary symptom of immunodeficiency but may be seen in certain autoimmune conditions.