ATI RN
ATI Pharmacology Proctored Exam 2023
1. A client has a new prescription for Amiodarone. Which of the following instructions should the nurse include?
- A. Take this medication with meals.
- B. Avoid drinking grapefruit juice.
- C. Take this medication at bedtime.
- D. Increase your intake of sodium-rich foods.
Correct answer: B
Rationale: The correct instruction the nurse should include is to advise the client to avoid drinking grapefruit juice while taking Amiodarone. Grapefruit juice can inhibit the metabolism of Amiodarone, leading to increased blood levels of the medication and raising the risk of adverse effects, such as cardiac toxicity. Choices A, C, and D are incorrect. Taking Amiodarone with meals, at bedtime, or increasing intake of sodium-rich foods are not necessary instructions for this medication.
2. A client is taking Desmopressin for Diabetes Insipidus. For which of the following adverse effects should the nurse monitor?
- A. Hypovolemia
- B. Hypercalcemia
- C. Agitation
- D. Headache
Correct answer: D
Rationale: Headache is an adverse effect that the nurse should monitor for in a client taking Desmopressin for Diabetes Insipidus. It can be an early sign of water intoxication, which is a potential complication of desmopressin therapy due to excessive water retention in the body.
3. When administering medications to a 4-month-old infant, which of the following pharmacokinetic principles should be considered? (Select all that apply.)
- A. Infants have a more rapid gastric emptying time.
- B. Infants have immature liver function.
- C. Infants' blood-brain barrier is poorly developed.
- D. Infants have an increased ability to absorb topical medications.
Correct answer: B
Rationale: When administering medications to a 4-month-old infant, the pharmacokinetic principle to consider is that infants have immature liver function until 1 year of age. This requires medications metabolized by the liver to be administered in smaller dosages. While infants do have a more rapid gastric emptying time, immature liver function is a more critical pharmacokinetic consideration in this context. Additionally, although infants have a poorly developed blood-brain barrier, this relates more to pharmacodynamic effects rather than pharmacokinetic principles. The statement about infants having an increased ability to absorb topical medications is not directly related to pharmacokinetic principles, making choice B the correct answer.
4. What information should you provide to your patient if they are taking sennosides? Select All That Apply.
- A. Sennosides should be used for short-term therapy
- B. The medication does not cure hypothyroidism
- C. The color of the urine may change to pink, red, violet, yellow, or brown
- D. Make sure to use other forms of bowel regulation
Correct answer: A
Rationale: When educating a patient taking sennosides, it is important to emphasize that these laxatives should be used for short-term therapy only. The medication does not address hypothyroidism, so this information is not relevant. Patients should be informed that the color of their urine may change to various colors like pink, red, violet, yellow, or brown, which is a common side effect of sennosides. It is advisable to incorporate other forms of bowel regulation alongside sennosides for optimal bowel health. Choice A is correct as it provides essential guidance on the duration of sennosides use. Choice B is incorrect because sennosides are not used to cure hypothyroidism. Choice C is correct as it highlights a common side effect of sennosides. Choice D is incorrect because it does not specifically relate to sennosides but rather suggests using other forms of bowel regulation in general.
5. A client is taking Ritonavir, a protease inhibitor, to treat HIV infection. The nurse should monitor for which of the following adverse effects?
- A. Increased TSH level
- B. Decreased ALT level
- C. Hypoglycemia
- D. Hyperlipidemia
Correct answer: D
Rationale: Hyperlipidemia, characterized by increased cholesterol and triglyceride levels, can occur as an adverse effect of Ritonavir. Monitoring lipid levels is essential to detect and manage this potential side effect in clients taking this medication for HIV infection.
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