a nurse is planning to administer iv alteplase to a client who is demonstrating manifestations of a massive pulmonary embolism which of the following

ATI RN

ATI Pharmacology Proctored Exam

1. A healthcare professional is planning to administer IV Alteplase to a client who is demonstrating manifestations of a massive Pulmonary Embolism. Which of the following interventions should the healthcare professional plan to take?

A. Administer IM Enoxaparin along with the Alteplase dose.
B. Hold direct pressure on puncture sites for up to 30 min.
C. Administer Aminocaproic acid IV prior to alteplase infusion.
D. Prepare to administer Alteplase within 8 hr of manifestation onset.

Correct answer: B

Rationale: The correct intervention when administering IV Alteplase is to hold direct pressure on puncture sites for 10 to 30 minutes or until oozing of blood stops. This helps prevent bleeding complications associated with thrombolytic therapy. Administering IM Enoxaparin is not indicated with Alteplase, as it is an anticoagulant rather than a thrombolytic agent. Aminocaproic acid is not typically administered prior to alteplase infusion in the context of a massive Pulmonary Embolism. While timely administration of Alteplase is important, the specific timeframe within which it should be administered may vary based on the clinical situation, so a strict 8-hour window is not universally applicable.

2. Which of the following is the antidote for benzodiazepine toxicity?

A. Flumazenil
B. Methylene blue
C. Deferoxamine
D. Alkalinize urine

Correct answer: A

Rationale: Flumazenil is the specific antidote for benzodiazepine toxicity. It acts as a competitive antagonist at the benzodiazepine binding site on the GABA receptor, reversing the sedative effects of benzodiazepines. Administration of flumazenil is indicated in cases of benzodiazepine overdose or toxicity to rapidly reverse the central nervous system depression caused by these drugs. It is important to note that flumazenil should be used cautiously in patients with a history of seizures or those who are physically dependent on benzodiazepines, as it can precipitate withdrawal symptoms or seizures.

3. A client with chronic myeloid leukemia is receiving hydroxyurea. Which of the following findings should the nurse monitor?

A. Hyperkalemia
B. Hypertension
C. Neutropenia
D. Tinnitus

Correct answer: C

Rationale: The nurse should monitor the client for neutropenia when receiving hydroxyurea, as it is a common adverse effect caused by bone marrow suppression. Neutropenia increases the risk of infections, making it crucial for the nurse to closely monitor the client's white blood cell count.

4. What classification of drug is Penicillin?

A. Antiarrhythmic
B. Anticonvulsant
C. Antibacterial
D. Mood stabilizer

Correct answer: C

Rationale: Penicillin is classified as an antibacterial drug, specifically used to treat bacterial infections. It works by inhibiting the growth of bacteria, making it an effective treatment for various bacterial infections. Choices A, B, and D are incorrect as Penicillin does not belong to these drug classifications. Penicillin does not have any direct effect on heart rhythm (antiarrhythmic), does not treat seizures (anticonvulsant), and is not used to stabilize mood (mood stabilizer).

5. A healthcare professional is preparing to administer morphine 4 mg IV to a client. Available is morphine 10 mg/mL. How many mL should the healthcare professional administer?

A. 0.2 mL
B. 0.4 mL
C. 0.6 mL
D. 0.8 mL

Correct answer: B

Rationale: To administer 4 mg from a solution of 10 mg/mL, the healthcare professional should administer 0.4 mL. The calculation is done by dividing the desired dose (4 mg) by the concentration of the solution (10 mg/mL), which equals 0.4 mL. Choice A (0.2 mL) is incorrect because it is half of the correct calculation. Choice C (0.6 mL) is incorrect because it is 50% more than the correct calculation. Choice D (0.8 mL) is incorrect because it exceeds the correct calculation.