ATI RN
ATI Pharmacology Proctored Exam
1. A client is receiving combination chemotherapy. Which of the following findings should the nurse identify as an indication of an oncologic emergency?
- A. Dry oral mucous membranes
- B. Nausea and vomiting
- C. Temperature of 38.1°C (100.6°F)
- D. Anorexia
Correct answer: C
Rationale: A temperature of 38.1°C (100.6°F) can indicate an infection, which is considered an oncologic emergency in clients receiving chemotherapy due to the increased risk of sepsis in immunocompromised individuals. Dry oral mucous membranes (Choice A), nausea and vomiting (Choice B), and anorexia (Choice D) are common side effects of chemotherapy but do not typically indicate an oncologic emergency requiring immediate intervention.
2. What does it mean when a medication has a half-life?
- A. It only lasts for 30 minutes after the medication is given
- B. How long it takes for half of the dose to be eliminated from the bloodstream
- C. It is the peak of how effective the medicine is
- D. Drug is greatly reduced before it reaches the systemic circulation
Correct answer: B
Rationale: When a medication has a half-life, it refers to the time it takes for half of the dose to be eliminated from the bloodstream. This parameter is crucial in understanding the duration of action and dosing intervals for medications in clinical practice. Choice A is incorrect as the half-life is not about how long the medication lasts but about elimination from the body. Choice C is incorrect because the half-life is not about the peak effectiveness of the medicine. Choice D is incorrect as it does not accurately define the concept of half-life.
3. What should a patient avoid while taking Angiotensin-converting enzymes?
- A. Salt substitutes
- B. Foods high in potassium
- C. Foods high in sodium
- D. All of the above
Correct answer: A
Rationale: Patients taking Angiotensin-converting enzyme (ACE) inhibitors should avoid salt substitutes because they can contain potassium chloride, which may lead to hyperkalemia. It is important to restrict potassium-rich foods while on ACE inhibitors, but the primary concern with salt substitutes is their potassium content.
4. A client has a prescription for hydrochlorothiazide to treat hypertension. The nurse should monitor the client for which of the following adverse effects?
- A. Hypokalemia
- B. Hypertension
- C. Hyperglycemia
- D. Hypercalcemia
Correct answer: A
Rationale: Hydrochlorothiazide is a diuretic that can cause potassium loss, leading to hypokalemia. Monitoring potassium levels is crucial to prevent potential adverse effects such as cardiac arrhythmias and muscle weakness.
5. A healthcare provider is educating a client who has a new prescription for Simvastatin. Which of the following instructions should the healthcare provider include?
- A. Take this medication with food.
- B. Avoid drinking grapefruit juice.
- C. Take this medication in the morning.
- D. Increase your intake of potassium-rich foods.
Correct answer: B
Rationale: The correct instruction that the healthcare provider should include is to 'Avoid drinking grapefruit juice.' Grapefruit juice can increase the blood levels of Simvastatin, leading to potential side effects like muscle pain and liver damage. Instructing the client to avoid grapefruit juice helps prevent these adverse effects and ensures the medication's efficacy. Choices A, C, and D are incorrect because taking Simvastatin with food, at a specific time, or increasing potassium-rich foods intake are not essential instructions for this medication.
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