ATI RN
Proctored Pharmacology ATI
1. What is the expected pharmacological action of propranolol?
- A. Block stimulation of beta1 receptors
- B. Alter water and electrolyte transport in the large intestine
- C. Block stimulation of beta2 receptors
- D. Both A and C are correct
Correct answer: D
Rationale: Propranolol exerts its pharmacological action by blocking stimulation of both beta1 and beta2 receptors. By doing so, it leads to decreased heart rate and blood pressure. Therefore, both options A and C are correct as propranolol affects both types of beta receptors. Choice B is incorrect as propranolol does not alter water and electrolyte transport in the large intestine.
2. Reteplase (Retavase) has been ordered for a client diagnosed with an MI. The nurse understands that this drug needs to be administered within which time frame following the onset of symptoms?
- A. 45 minutes to 18 hours
- B. 30 minutes to 12 hours
- C. 90 minutes to 36 hours
- D. 60 minutes to 24 hours
Correct answer: B
Rationale: Reteplase (Retavase) is a thrombolytic medication used in the treatment of myocardial infarction (MI). It is crucial to administer this drug within 30 minutes to 12 hours following the onset of symptoms to achieve optimal therapeutic effects and improve patient outcomes. Administering Reteplase within this time frame helps in restoring blood flow to the affected areas of the heart by dissolving blood clots, reducing myocardial damage, and potentially preventing further complications associated with MI.
3. A client has a new prescription for Etravirine, an NNRTI. Which of the following statements should the nurse include in teaching the client?
- A. Take this medication with food.
- B. Take this medication on an empty stomach.
- C. Take this medication at the same time every day.
- D. Take this medication at bedtime to prevent drowsiness.
Correct answer: C
Rationale: The correct statement the nurse should include in teaching the client is to take Etravirine at the same time every day. This ensures consistent blood levels and effectiveness of the medication. Consistent timing is essential to achieve optimal therapeutic effects and avoid missing doses. Choices A and B are incorrect because Etravirine should not necessarily be taken with or without food; it is more important to take it consistently. Choice D is incorrect as there is no need to take Etravirine at bedtime to prevent drowsiness.
4. A client is taking lisinopril. Which of the following outcomes indicates a therapeutic effect of the medication?
- A. Decreased blood pressure
- B. Increase in HDL cholesterol
- C. Prevention of bipolar manic episodes
- D. Improved sexual function
Correct answer: A
Rationale: The therapeutic effect of lisinopril, an ACE inhibitor, is indicated by a decrease in blood pressure. Lisinopril works by relaxing blood vessels, leading to a reduction in blood pressure. Monitoring and achieving a decrease in blood pressure is a key outcome when managing hypertension with lisinopril. Choices B, C, and D are incorrect because lisinopril is not intended to increase HDL cholesterol, prevent bipolar manic episodes, or improve sexual function. Therefore, the correct outcome indicating the therapeutic effect of lisinopril is a decrease in blood pressure.
5. A client has a new prescription for hydrochlorothiazide. The client should monitor for which of the following adverse effects?
- A. Hyponatremia
- B. Ototoxicity
- C. Hypoglycemia
- D. Hyperkalemia
Correct answer: A
Rationale: Hyponatremia is a potential adverse effect of hydrochlorothiazide due to its diuretic action. Hydrochlorothiazide is a thiazide diuretic that can cause sodium and water loss, potentially leading to hyponatremia. Monitoring for symptoms such as weakness, confusion, and muscle cramps can help detect hyponatremia early. Ototoxicity (choice B) is not a common adverse effect of hydrochlorothiazide. Hypoglycemia (choice C) is not typically associated with hydrochlorothiazide use. Hyperkalemia (choice D) is more commonly associated with potassium-sparing diuretics rather than thiazide diuretics like hydrochlorothiazide.
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