what is the action of metformin

ATI RN

ATI Pharmacology Test Bank

1. What is the action of Metformin?

A. Decreasing intestinal glucose absorption
B. Increasing sensitivity to insulin
C. Decreasing hepatic glucose production
D. All of the above

Correct answer: D

Rationale: Metformin exerts its effects by decreasing hepatic glucose production, increasing sensitivity to insulin, and decreasing intestinal glucose absorption. These actions help in lowering blood glucose levels and improving insulin sensitivity in individuals with diabetes.

2. A client has a new prescription for Atorvastatin. Which of the following instructions should the nurse include?

A. Avoid drinking grapefruit juice.
B. Take the medication with your evening meal.
C. Increase your intake of leafy green vegetables.
D. Stop taking the medication if you experience muscle pain.

Correct answer: A

Rationale: The correct answer is A: 'Avoid drinking grapefruit juice.' Grapefruit juice should be avoided when taking Atorvastatin because it can increase the blood levels of the medication, potentially leading to a higher risk of adverse effects like muscle pain and liver damage. It is important to follow this instruction to ensure the safe and effective use of Atorvastatin. Choices B, C, and D are incorrect. Taking Atorvastatin with food, specifically a low-fat meal, is recommended, but it is not necessary to specify the evening meal. While increasing intake of leafy green vegetables is generally beneficial for health, it is not a specific instruction for Atorvastatin. Lastly, stopping the medication if one experiences muscle pain is not advisable without consulting a healthcare provider, as muscle pain can be a symptom of a serious side effect of Atorvastatin that requires medical attention.

3. A healthcare professional is providing discharge instructions to a client who has a new prescription for Furosemide. Which of the following instructions should the healthcare professional include?

A. Take the medication with breakfast.
B. Increase intake of foods high in potassium.
C. Avoid prolonged sun exposure.
D. Limit sodium intake.

Correct answer: B

Rationale: The correct answer is B: 'Increase intake of foods high in potassium.' Furosemide, a loop diuretic, can cause potassium depletion. The healthcare professional should instruct the client to increase the intake of foods high in potassium to prevent hypokalemia, a potential side effect of Furosemide therapy. Choice A is incorrect as Furosemide is usually recommended to be taken in the morning to prevent nocturia. Choice C is unrelated to the side effects of Furosemide. Choice D, while important for overall health, is not directly related to the side effects of Furosemide.

4. How do ACE inhibitors work?

A. Block the vasoconstrictor and aldosterone effects of angiotensin II at the receptor site
B. Block stimulation of beta 1 and beta 2 at the receptor sites
C. Block the conversion of angiotensin I to the vasoconstrictor angiotensin II
D. None of the above

Correct answer: C

Rationale: ACE inhibitors work by inhibiting the conversion of angiotensin I to angiotensin II. Angiotensin II is a potent vasoconstrictor, and by blocking its production, ACE inhibitors help dilate blood vessels, reduce blood pressure, and decrease the workload of the heart. Choice A is incorrect because it describes the mechanism of action of angiotensin receptor blockers (ARBs), not ACE inhibitors. Choice B is incorrect as it describes beta-blockers, not ACE inhibitors. Choice D is incorrect as ACE inhibitors do have a specific mechanism of action.

5. A healthcare provider is reviewing a client's medication history and notes a new prescription for Enalapril. The healthcare provider should monitor the client for which of the following as an adverse effect of this medication?

A. Bradycardia
B. Hyperkalemia
C. Hypoglycemia
D. Hypocalcemia

Correct answer: B

Rationale: Enalapril, an ACE inhibitor, can cause hyperkalemia as an adverse effect due to decreased aldosterone levels, leading to potassium retention. Monitoring potassium levels is essential to prevent complications associated with hyperkalemia. Bradycardia (Choice A) is not a common adverse effect of Enalapril. Enalapril does not typically affect glucose levels, so hypoglycemia (Choice C) is not a common concern with this medication. Enalapril does not directly impact calcium levels, so hypocalcemia (Choice D) is not a typical adverse effect.