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ATI Pathophysiology Test Bank
1. DiGeorge syndrome is a primary immune deficiency caused by:
- A. Failure of B cells to mature
- B. Congenital lack of thymic tissue
- C. Failure of formed elements of blood to develop
- D. Selective IgG deficiency
Correct answer: B
Rationale: DiGeorge syndrome is caused by a congenital lack of thymic tissue, which plays a crucial role in T cell development and maturation, leading to immune deficiency. Choice A is incorrect because DiGeorge syndrome primarily affects T cells, not B cells. Choice C is incorrect as it is too broad and not specific to the thymus. Choice D is incorrect as selective IgG deficiency is a different condition unrelated to DiGeorge syndrome.
2. Multiple sclerosis manifests as asymmetrical and in different parts of the body because:
- A. Autoreactive lymphocytes are causing diffuse patchy damage to the myelin sheath in the central nervous system.
- B. Acetylcholine receptors are destroyed by immunoglobulin G.
- C. Autoreactive T lymphocytes cause progressive loss of neurons in the substantia nigra.
- D. Cortical motor cells degenerate.
Correct answer: A
Rationale: The correct answer is A. Multiple sclerosis is characterized by the immune system attacking the myelin sheath in the central nervous system. This attack leads to patchy damage on the myelin sheath, resulting in asymmetrical neurological symptoms. Choices B, C, and D are incorrect because they do not accurately describe the pathophysiology of multiple sclerosis. In multiple sclerosis, it is the autoreactive lymphocytes that target and damage the myelin sheath, not acetylcholine receptors, T lymphocytes, or cortical motor cells.
3. Which manifestation of stress reflects the non-specific fight or flight response?
- A. Decreased pupillary light response
- B. Increased GI motility
- C. Decreased short-term memory
- D. Increased cardiopulmonary rates
Correct answer: D
Rationale: The correct answer is D, 'Increased cardiopulmonary rates.' The fight or flight response, activated by stress, is a non-specific physiological reaction that prepares the body to deal with perceived threats. In this response, the heart rate and breathing rate increase to supply more oxygen to muscles and vital organs, enabling a rapid response in dangerous situations. Choices A, B, and C are incorrect because decreased pupillary light response, increased GI motility, and decreased short-term memory are not typical manifestations of the fight or flight response.
4. Which of the following is a characteristic of disseminated intravascular coagulation (DIC)?
- A. Simultaneous stroke and heart attack
- B. Simultaneous clotting and bleeding
- C. Simultaneous clotting and insulin release
- D. Simultaneous bleeding and vomiting
Correct answer: B
Rationale: Disseminated intravascular coagulation (DIC) is characterized by simultaneous clotting and bleeding throughout the body. This imbalance in the body's clotting system leads to the formation of blood clots in small blood vessels, which can consume clotting factors and platelets, ultimately leading to excessive bleeding. Choices A, C, and D are incorrect because they do not describe the characteristic feature of DIC, which involves both clotting and bleeding.
5. A group of nursing students at Nurseslabs University is currently learning about family violence. Which of the following is true about the topic mentioned?
- A. Family violence affects every socioeconomic level.
- B. Family violence is caused by drugs and alcohol abuse.
- C. Family violence predominantly occurs in lower socioeconomic levels.
- D. Family violence rarely occurs during pregnancy.
Correct answer: A
Rationale: The correct answer is A: Family violence affects individuals across all socioeconomic levels. Family violence is not limited to any specific socioeconomic level; it can happen in any family, regardless of their economic status. Choice B is incorrect because while substance abuse can contribute to family violence, it is not the sole cause. Choice C is incorrect as family violence can occur in families from all socioeconomic backgrounds. Choice D is incorrect as family violence can indeed occur during pregnancy, posing serious risks to both the mother and the unborn child.
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