ATI RN
Pathophysiology Final Exam
1. An oncology nurse is providing care for an adult patient who is currently immunocompromised. The nurse is aware of the physiology involved in hematopoiesis and immune function, including the salient role of cytokines. What is the primary role of cytokines in maintaining homeostasis?
- A. Cytokines perform phagocytosis in response to bacterial and protozoal infections.
- B. Cytokines perform a regulatory role in the development of diverse blood cells.
- C. Cytokines play a significant role in the formation of all blood cells.
- D. Cytokines are produced in response to the presence of antibodies.
Correct answer: B
Rationale: The primary role of cytokines in maintaining homeostasis is to perform a regulatory function in the development of diverse blood cells. Cytokines act as signaling molecules that regulate the immune response and hematopoiesis. Choice A is incorrect because cytokines do not perform phagocytosis; they regulate immune responses. Choice C is incorrect because while cytokines are involved in the formation of some blood cells, they are not considered the basic 'building blocks' of all blood cells. Choice D is incorrect because cytokines are not formed in response to antibodies, but rather play a role in the immune response to various stimuli.
2. What is the process of moving air into the lungs with subsequent distribution to the alveoli called?
- A. Ventilation
- B. Aeration
- C. Enclosure vapor
- D. Residual volume
Correct answer: A
Rationale: The correct answer is A: Ventilation. Ventilation is the process of moving air into the lungs and distributing it to the alveoli for gas exchange. Choice B, Aeration, is not the correct term for this specific process. Choice C, Enclosure vapor, is not related to the movement of air into the lungs. Choice D, Residual volume, refers to the amount of air left in the lungs after maximal expiration and is not the process of moving air into the lungs.
3. A child's thymus gland is fully formed and proportionately larger than an adult's. Which of the following processes that contribute to immunity takes place in the thymus gland?
- A. Differentiation of B cells
- B. Production of natural killer (NK) cells
- C. Proliferation of T cells
- D. Filtration of antigens from the blood
Correct answer: C
Rationale: The correct answer is C: Proliferation of T cells. The thymus gland is responsible for the maturation and proliferation of T cells, which play a crucial role in adaptive immunity. Option A, differentiation of B cells, is incorrect because B cell maturation primarily occurs in the bone marrow. Option B, production of natural killer (NK) cells, is incorrect as NK cells are mainly produced in the bone marrow and lymph nodes. Option D, filtration of antigens from the blood, is incorrect as antigen filtration is not a primary function of the thymus gland.
4. Which of the following types of vitamin or mineral deficiency can cause megaloblastic anemia and is associated with lower extremity paresthesias?
- A. Vitamin B12
- B. Folate
- C. Iron
- D. Vitamin K
Correct answer: A
Rationale: The correct answer is Vitamin B12. Vitamin B12 deficiency can lead to megaloblastic anemia, a condition characterized by the production of abnormally large and immature red blood cells. Lower extremity paresthesias, such as tingling or numbness, are common neurological symptoms associated with vitamin B12 deficiency. Folate deficiency can also cause megaloblastic anemia but is not typically linked to lower extremity paresthesias. Iron deficiency leads to microcytic anemia, not megaloblastic anemia. Vitamin K deficiency is associated with bleeding tendencies, not megaloblastic anemia or paresthesias.
5. What is the most appropriate nursing diagnosis for the client's son based on the information provided?
- A. Risk for other-directed violence
- B. Disturbed sleep pattern
- C. Caregiver role strain
- D. Social isolation
Correct answer: C
Rationale: The correct answer is 'Caregiver role strain.' In the scenario presented, the son expresses that his father's constant confusion, incontinence, and tendency to wander are intolerable. These challenges indicate that the son is experiencing strain in his role as a caregiver. 'Risk for other-directed violence' is not appropriate because there is no indication of violent behavior. 'Disturbed sleep pattern' is not the most relevant nursing diagnosis given the information provided. 'Social isolation' is not the most appropriate choice as the son's concerns are related to the challenges of caregiving, not isolation.
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