ATI RN
ATI Pathophysiology Quizlet
1. An older adult patient has just sheared the skin on her elbow while attempting to boost herself up in bed, an event that has precipitated acute inflammation in the region surrounding the wound. Which of the following events will occur during the vascular stage of the patient's inflammation?
- A. Outpouring of exudate into interstitial spaces
- B. Chemotaxis
- C. Accumulation of leukocytes along epithelium
- D. Phagocytosis of cellular debris
Correct answer: A
Rationale: During the vascular stage of inflammation, there is an outpouring of exudate into the interstitial spaces, leading to swelling and edema. Choice B, chemotaxis, occurs during the cellular stage of inflammation, where leukocytes move to the site of injury in response to chemical signals. Choice C, accumulation of leukocytes along the epithelium, is not a typical event during the vascular stage. Phagocytosis of cellular debris, as in choice D, mainly occurs during the resolution stage of inflammation.
2. A patient is being treated for active tuberculosis with ethambutol (Myambutol). The patient states to the nurse that he cannot identify the red and green on the traffic lights when he is driving. Based on this finding, what medical intervention is most appropriate?
- A. Assess for photosensitivity.
- B. Discontinue ethambutol (Myambutol).
- C. Decrease the ethambutol (Myambutol) dose.
- D. Administer vitamin B.
Correct answer: A
Rationale: The correct answer is to assess for photosensitivity. Ethambutol can cause optic neuritis, leading to visual disturbances, including difficulty differentiating red and green colors. This is a sign of optic nerve damage and requires immediate evaluation. Discontinuing ethambutol may be necessary if optic neuritis is confirmed, but this decision should be made by a healthcare provider. Decreasing the dose of ethambutol may not address the visual changes. Administering vitamin B does not directly address the side effect caused by ethambutol.
3. An adult patient has begun treatment with fluconazole. The nurse should recognize the need to likely discontinue the drug if the patient develops which of the following signs or symptoms?
- A. Jaundice
- B. Weight gain
- C. Iron deficiency anemia
- D. Hematuria
Correct answer: A
Rationale: The correct answer is A: Jaundice. Fluconazole, an antifungal medication, can rarely cause hepatotoxicity, which may manifest as jaundice. Monitoring for signs of liver dysfunction, such as jaundice, is crucial during fluconazole therapy. Weight gain, iron deficiency anemia, and hematuria are not commonly associated with fluconazole use and are not indications for discontinuing the drug.
4. Peritonitis is a condition that can result in serious complications. Identify one of the complications.
- A. Increased peristalsis
- B. Dizziness and malaise
- C. Sepsis and shock
- D. Nausea and vomiting
Correct answer: C
Rationale: Corrected Rationale: Peritonitis can lead to severe complications such as sepsis and shock due to the infection spreading in the abdominal cavity. Sepsis is a systemic inflammatory response to infection, and shock is a life-threatening condition where the body's organs are not receiving enough blood flow. Choices A, B, and D are incorrect. Increased peristalsis is not a typical complication of peritonitis; dizziness and malaise, as well as nausea and vomiting, are symptoms rather than complications of the condition.
5. A patient has a heart attack that leads to progressive cell injury resulting in cell death with severe cell swelling and breakdown of organelles. What term would the nurse use to define this process?
- A. Adaptation
- B. Pathologic calcification
- C. Apoptosis
- D. Necrosis
Correct answer: D
Rationale: The correct answer is D: Necrosis. Necrosis is the process of cell death characterized by cell swelling, breakdown of organelles, and eventual rupture, often following ischemic injury like a heart attack. Choices A, B, and C are incorrect. Adaptation refers to the ability of cells to adjust to changes in their environment. Pathologic calcification is the abnormal deposition of calcium salts in tissues. Apoptosis is a programmed cell death that occurs in a controlled, orderly manner.
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