ATI RN
ATI Pathophysiology
1. A patient has been diagnosed with cytomegalovirus (CMV). Which of the following drugs would be ineffective in the treatment of this disease?
- A. Ribavirin (Rebetol)
- B. Ganciclovir (Cytovene) IV
- C. Foscarnet (Foscavir) IV
- D. Valganciclovir hydrochloride (Valcyte)
Correct answer: A
Rationale: The correct answer is A, Ribavirin (Rebetol). Ribavirin is not effective against CMV. Choice B, Ganciclovir (Cytovene) IV, is a common treatment for CMV as it inhibits viral DNA synthesis. Choice C, Foscarnet (Foscavir) IV, is also used for CMV infections by blocking viral DNA polymerase. Choice D, Valganciclovir hydrochloride (Valcyte), is a prodrug of Ganciclovir and is effective against CMV. Therefore, Ribavirin is the drug that would be ineffective in treating CMV.
2. A 60-year-old male patient is receiving androgen therapy for the treatment of hypogonadism. Which of the following adverse effects should the nurse monitor for?
- A. Hepatotoxicity
- B. Nephrotoxicity
- C. Cardiotoxicity
- D. Pulmonary toxicity
Correct answer: A
Rationale: The correct answer is A: Hepatotoxicity. Androgen therapy, such as testosterone, can lead to hepatotoxicity, which is toxic to the liver. Therefore, the nurse should monitor the patient's liver function. Choices B, C, and D are incorrect because androgen therapy is not typically associated with nephrotoxicity, cardiotoxicity, or pulmonary toxicity.
3. A male patient with benign prostatic hyperplasia (BPH) is prescribed finasteride (Proscar). What should the nurse include in the patient education?
- A. The medication is expected to reduce the size of the prostate, which should improve urinary symptoms over time.
- B. The medication will improve symptoms within a few days.
- C. The medication will cure BPH after treatment is complete.
- D. The medication may cause erectile dysfunction as a side effect.
Correct answer: A
Rationale: Finasteride is expected to reduce the size of the prostate, which should improve urinary symptoms over time, although the effects may take several weeks or months to become noticeable.
4. A patient is prescribed medroxyprogesterone acetate (Provera) for the treatment of endometriosis. What key instruction should the nurse provide regarding the administration of this medication?
- A. Take the medication at the same time each day to maintain consistent hormone levels.
- B. Discontinue the medication if side effects occur.
- C. Take the medication with food to prevent gastrointestinal upset.
- D. Apply the medication once a week.
Correct answer: A
Rationale: The correct instruction for medroxyprogesterone acetate (Provera) is to take the medication at the same time each day to maintain consistent hormone levels and ensure its effectiveness. Choice B is incorrect because discontinuing the medication abruptly without consulting healthcare providers can be harmful. Choice C is incorrect as taking the medication with food is not necessary for this specific drug. Choice D is incorrect as medroxyprogesterone is typically taken orally, not applied topically.
5. After studying about fungi, which information indicates a correct understanding of fungi? Fungi causing deep or systemic infections:
- A. Are easily treated with penicillin
- B. Are extremely rare
- C. Never occur with other infections
- D. Are commonly opportunistic
Correct answer: D
Rationale: The correct answer is D: 'Are commonly opportunistic.' Fungi causing deep or systemic infections are commonly opportunistic, particularly in individuals with compromised immune systems. Choice A is incorrect because fungi infections are not easily treated with penicillin. Choice B is incorrect as deep or systemic fungal infections are not extremely rare. Choice C is incorrect as fungal infections can co-occur with other infections.
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