ATI RN
ATI Pathophysiology
1. A patient has been diagnosed with cytomegalovirus (CMV). Which of the following drugs would be ineffective in the treatment of this disease?
- A. Ribavirin (Rebetol)
- B. Ganciclovir (Cytovene) IV
- C. Foscarnet (Foscavir) IV
- D. Valganciclovir hydrochloride (Valcyte)
Correct answer: A
Rationale: The correct answer is A, Ribavirin (Rebetol). Ribavirin is not effective against CMV. Choice B, Ganciclovir (Cytovene) IV, is a common treatment for CMV as it inhibits viral DNA synthesis. Choice C, Foscarnet (Foscavir) IV, is also used for CMV infections by blocking viral DNA polymerase. Choice D, Valganciclovir hydrochloride (Valcyte), is a prodrug of Ganciclovir and is effective against CMV. Therefore, Ribavirin is the drug that would be ineffective in treating CMV.
2. Which physiologic response is most likely to accompany activation of the parasympathetic nervous system?
- A. Increased heart rate
- B. Increased gastric motility
- C. Pupil dilation
- D. Sweating
Correct answer: B
Rationale: The correct answer is B: Increased gastric motility. The parasympathetic nervous system is known to promote rest and digest functions, which includes increasing gastric motility to aid in digestion. Choices A, C, and D are incorrect as they are more characteristic of the sympathetic nervous system. The sympathetic nervous system is responsible for the fight or flight response, leading to increased heart rate (Choice A), pupil dilation (Choice C), and sweating (Choice D) among other responses.
3. A patient has been prescribed clomiphene citrate (Clomid) for infertility. What should the nurse include in the teaching plan about the use of this medication?
- A. Clomiphene is taken daily for 5 days at the beginning of the menstrual cycle.
- B. Clomiphene is taken once daily throughout the menstrual cycle.
- C. Clomiphene is taken twice daily for 5 days at the end of the menstrual cycle.
- D. Clomiphene is taken three times daily for 10 days at the beginning of the menstrual cycle.
Correct answer: A
Rationale: Corrected Rationale: Clomiphene is typically taken daily for 5 days at the beginning of the menstrual cycle to stimulate ovulation. Choice A is the correct answer because it aligns with the standard dosing regimen for clomiphene citrate. Choices B, C, and D provide incorrect information about the dosing schedule for clomiphene, which can lead to ineffective treatment and potential side effects. Choice B suggests continuous daily intake, which is not the standard practice for clomiphene. Choice C and D mention different dosing frequencies and timings, which are not in line with the typical protocol for using clomiphene for infertility.
4. A patient is prescribed tadalafil (Cialis) for erectile dysfunction. What specific contraindication should the nurse discuss with the patient?
- A. History of hypertension
- B. Use of nitrates
- C. Use of antihypertensive medications
- D. History of peptic ulcer disease
Correct answer: B
Rationale: The correct answer is B: 'Use of nitrates.' Tadalafil (Cialis) is contraindicated in patients taking nitrates due to the risk of severe hypotension. Nitrates and Cialis both cause vasodilation, which can lead to a dangerous drop in blood pressure when used together. Choices A, C, and D are incorrect because a history of hypertension, use of antihypertensive medications, and a history of peptic ulcer disease are not specific contraindications for tadalafil use.
5. A nurse practitioner is seeing a client in the clinic with a suspected diagnosis of bacterial meningitis. What should the nurse anticipate as the priority action?
- A. Administer the first dose of antibiotics immediately after blood cultures are drawn.
- B. Start an IV line and administer corticosteroids to reduce inflammation.
- C. Isolate the client to prevent the spread of infection.
- D. Perform a lumbar puncture to confirm the diagnosis.
Correct answer: A
Rationale: The correct answer is to administer the first dose of antibiotics immediately after blood cultures are drawn for suspected bacterial meningitis. This is crucial to initiate treatment promptly and improve patient outcomes. Starting an IV line and administering corticosteroids (Choice B) may be part of the treatment plan but administering antibiotics is the priority. Isolating the client (Choice C) is important to prevent the spread of infection but not the priority over initiating antibiotic therapy. Performing a lumbar puncture (Choice D) may confirm the diagnosis, but treatment should not be delayed for this step in suspected cases of bacterial meningitis.
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