ATI RN
ATI Pharmacology
1. A healthcare professional reviewing a client's medical record notes a new prescription for verifying the trough level of the client's medication. Which of the following actions should the professional take?
- A. Obtain a blood specimen immediately prior to administering the next dose of medication.
- B. Verify that the client has been taking the medication for 24 hours before obtaining a blood specimen.
- C. Ask the client to provide a urine specimen after the next dose of medication.
- D. Administer the medication, and obtain a blood specimen 30 minutes later.
Correct answer: A
Rationale: To verify trough levels of a medication, the healthcare professional should obtain a blood specimen immediately before administering the next dose of medication. This timing ensures an accurate representation of the medication's lowest concentration in the bloodstream, which is crucial for therapeutic monitoring and dose adjustments. Choice B is incorrect because waiting 24 hours after taking the medication would not provide an accurate trough level. Choice C is incorrect as urine specimens are not used to measure trough levels. Choice D is incorrect because obtaining a blood specimen 30 minutes after administering the medication would not reflect the trough level, as it is the lowest concentration before the next dose.
2. A client is being discharged with a new prescription for furosemide 40 mg PO daily. Which of the following instructions should be included?
- A. Avoid foods rich in potassium.
- B. Take the medication with food.
- C. Weigh yourself daily.
- D. Stand up slowly to minimize orthostatic hypotension.
Correct answer: D
Rationale: The correct answer is D: 'Stand up slowly to minimize orthostatic hypotension.' Clients prescribed furosemide are at risk for orthostatic hypotension, a sudden drop in blood pressure when changing positions. Advising the client to stand up slowly can help prevent this complication. Instructing the client to avoid rapid position changes decreases the likelihood of dizziness or fainting episodes. Choices A, B, and C are incorrect because furosemide does not require avoiding potassium-rich foods, taking the medication with food, or daily weighing as specific instructions.
3. A client has a new prescription for Lisinopril. Which of the following laboratory values should be monitored?
- A. Serum potassium
- B. Serum sodium
- C. Serum calcium
- D. Serum magnesium
Correct answer: A
Rationale: Corrected Rationale: Lisinopril is an ACE inhibitor that can cause hyperkalemia by reducing potassium excretion through the kidneys. Monitoring serum potassium levels is crucial to detect hyperkalemia early and prevent adverse effects such as cardiac arrhythmias. Choices B, C, and D are incorrect because Lisinopril is not known to significantly impact sodium, calcium, or magnesium levels in the same way it affects potassium levels.
4. A healthcare professional is reviewing the medication list of a client who has a new prescription for Metformin to treat type 2 diabetes. Which of the following medications should the healthcare professional identify as placing the client at risk for lactic acidosis?
- A. Metformin
- B. Metoprolol
- C. Lisinopril
- D. Insulin
Correct answer: A
Rationale: Metformin is known to have a risk of causing lactic acidosis, particularly in clients with renal impairment or predisposing conditions. Lactic acidosis is a rare but serious adverse effect of metformin use that can be life-threatening. Metoprolol, Lisinopril, and Insulin do not have a known association with lactic acidosis. Healthcare professionals should monitor clients prescribed metformin carefully, especially those with risk factors, to detect and manage lactic acidosis promptly.
5. Which of the following is commonly used to treat migraine headaches?
- A. Beta-blockers
- B. Cholinesterase Inhibitors
- C. ACE inhibitors
- D. Anti-epileptic drugs (AEDs)
Correct answer: D
Rationale: Anti-epileptic drugs (AEDs) are often used in the management of migraine headaches due to their ability to help prevent or reduce the frequency and intensity of migraines. They work by stabilizing electrical activity in the brain, which can help in controlling migraine symptoms. While beta-blockers are also sometimes used in migraine prevention, anti-epileptic drugs are more commonly associated with migraine treatment. Cholinesterase Inhibitors are not typically used for migraine headaches, as they are more commonly associated with conditions like Alzheimer's disease. ACE inhibitors are a type of medication used to treat conditions like high blood pressure and heart failure, but they are not a first-line treatment for migraines.
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