ATI RN
Proctored Pharmacology ATI
1. A client has a new prescription for Amlodipine. Which of the following instructions should the nurse include during discharge teaching?
- A. Take the medication at bedtime.
- B. Avoid drinking grapefruit juice.
- C. Increase your intake of high-sodium foods.
- D. Expect a dry cough.
Correct answer: B
Rationale: The correct instruction for the nurse to include during discharge teaching is to advise the client to avoid drinking grapefruit juice. Grapefruit juice can inhibit the metabolism of amlodipine, a calcium channel blocker, leading to increased drug levels in the blood. This can result in potentiated side effects and potential toxicity. Option A is incorrect as amlodipine is usually taken once daily, not specifically at bedtime. Option C is incorrect because high-sodium foods are generally discouraged in individuals with hypertension. Option D is incorrect as a dry cough is not an expected side effect of amlodipine.
2. A client with Hodgkin's disease is receiving Cyclophosphamide IV. Which medication should be administered concurrently to prevent an adverse effect of Cyclophosphamide?
- A. Uroprotectant agent, such as mesna
- B. Opioid, such as morphine
- C. Loop diuretic, such as furosemide
- D. H1 receptor antagonist, such as diphenhydramine
Correct answer: A
Rationale: Mesna, an uroprotectant agent, is administered with nitrogen mustard chemotherapy drugs like Cyclophosphamide to prevent hemorrhagic cystitis, a common adverse effect. Mesna works by binding to and inactivating the toxic metabolites of Cyclophosphamide in the bladder, thereby reducing the risk of bladder toxicity.
3. What is one of the therapeutic uses of Valproate?
- A. Suppression of seizure activity
- B. Replacement of hypothyroidism to restore normal hormone balance
- C. Maintenance of blood glucose
- D. Lowering of blood pressure
Correct answer: A
Rationale: Valproate, also known as Valproic acid, is commonly used in medicine for the suppression of seizure activity. It is an anticonvulsant medication that helps manage and prevent seizures in various conditions such as epilepsy. While it is not used for replacing hypothyroidism, maintaining blood glucose levels, or lowering blood pressure, its primary therapeutic use is in managing seizures.
4. When teaching a client with a new prescription for Lithium, which instruction should the nurse include?
- A. Restrict fluid intake to 1,000 mL per day.
- B. Maintain a consistent sodium intake.
- C. Take the medication at bedtime.
- D. Expect to have frequent headaches.
Correct answer: B
Rationale: Maintaining a consistent sodium intake is crucial when taking Lithium to help regulate lithium levels in the body and prevent toxicity. Sodium levels can impact the effectiveness and safety of Lithium therapy. Restricting fluid intake to 1,000 mL per day (Choice A) is not appropriate and could lead to dehydration. Taking the medication at bedtime (Choice C) may vary depending on the individual's schedule but is not a critical instruction. Expecting to have frequent headaches (Choice D) is not a common side effect of Lithium.
5. A client has a new prescription for hydrochlorothiazide to treat hypertension. Which of the following instructions should be included?
- A. Take the medication in the morning.
- B. Increase intake of potassium-rich foods.
- C. Avoid sun exposure while taking this medication.
- D. Limit fluid intake to 1 liter per day.
Correct answer: B
Rationale: The correct instruction that should be included for a client prescribed hydrochlorothiazide is to increase the intake of potassium-rich foods. Hydrochlorothiazide, being a diuretic, can lead to hypokalemia by enhancing potassium excretion. Increasing consumption of potassium-rich foods like bananas or oranges can help prevent hypokalemia and maintain electrolyte balance. Choices A, C, and D are incorrect. Taking the medication in the morning is not a specific instruction related to hydrochlorothiazide. Avoiding sun exposure is more relevant for photosensitive medications, not hydrochlorothiazide. Limiting fluid intake to 1 liter per day is not necessary unless specifically advised by a healthcare provider.
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