ATI RN
ATI Pharmacology Proctored Exam
1. A client who is receiving combination chemotherapy is exhibiting a temperature of 38.1°C (100.6°F). Which of the following findings should the nurse identify as an indication of an oncologic emergency?
- A. Dry oral mucous membranes
- B. Nausea and vomiting
- C. Temperature of 38.1°C (100.6°F)
- D. Anorexia
Correct answer: C
Rationale: A temperature of 38.1°C (100.6°F) can indicate an infection, which is considered an oncologic emergency in clients undergoing chemotherapy due to the heightened risk of sepsis in immunocompromised individuals. Immediate assessment and intervention are crucial to prevent severe complications. Dry oral mucous membranes, nausea and vomiting, and anorexia are common side effects of chemotherapy but are not specific indicators of an oncologic emergency like a fever in this setting.
2. What is pharmacodynamics?
- A. The medical reference summarizing standards of drug purity, strength, and directions for synthesis
- B. The drug's actions at receptor sites and the physiological, chemical, and behavioral effects produced by these actions
- C. The maximum response that a drug can produce
- D. Movements of the drugs throughout the body
Correct answer: B
Rationale: Pharmacodynamics refers to the drug's actions at receptor sites and the physiological, chemical, and behavioral effects produced by these actions. It involves understanding how drugs interact with the body at the molecular level to produce their effects, including mechanisms of action, receptor binding, and downstream physiological responses. Choice A is incorrect because it describes pharmacopeia, which is a reference book containing standards for drugs. Choice C refers to efficacy, which is the maximum effect a drug can produce. Choice D describes pharmacokinetics, which focuses on the movement of drugs within the body.
3. A client has a prescription for Bethanechol to treat urinary retention. Which of the following findings is a manifestation of muscarinic stimulation?
- A. Dry mouth
- B. Hypertension
- C. Excessive perspiration
- D. Fecal impaction
Correct answer: C
Rationale: The correct answer is C: Excessive perspiration. Bethanechol is a muscarinic agonist that stimulates muscarinic receptors. Activation of muscarinic receptors can lead to excessive perspiration (diaphoresis) due to increased cholinergic activity, affecting sweat glands. Dry mouth, hypertension, and fecal impaction are not typically associated with muscarinic stimulation. Dry mouth is more commonly associated with anticholinergic medications, hypertension can be a result of alpha-adrenergic stimulation, and fecal impaction is not a direct effect of muscarinic receptor activation.
4. A patient is receiving education about a new prescription for Omeprazole to manage heartburn. What information should the nurse include in the teaching?
- A. Take this medication at bedtime.
- B. This medication decreases the production of gastric acid.
- C. Take this medication 2 hours after eating.
- D. This medication can cause hyperkalemia.
Correct answer: B
Rationale: The correct information to include when teaching a patient about Omeprazole is that it decreases the production of gastric acid. Omeprazole works by inhibiting the proton pump in the stomach lining, thereby reducing acid secretion. This mechanism helps in managing heartburn symptoms effectively. Choice A is incorrect because Omeprazole is usually taken before a meal. Choice C is incorrect as Omeprazole is typically taken before meals, not after. Choice D is incorrect because hyperkalemia is not a common side effect of Omeprazole.
5. A healthcare professional is preparing to administer Butorphanol to a client who has a history of substance use disorder. The healthcare professional should identify which of the following information as true regarding Butorphanol?
- A. Butorphanol has a greater risk of abuse than morphine.
- B. Butorphanol causes a higher incidence of respiratory depression than morphine.
- C. Butorphanol cannot be reversed with an opioid antagonist.
- D. Butorphanol can cause abstinence syndrome in opioid-dependent clients.
Correct answer: D
Rationale: Corrected Rationale: Butorphanol, an opioid agonist/antagonist, can lead to abstinence syndrome in clients who are opioid-dependent. This syndrome may present with symptoms like abdominal pain, fever, and anxiety. It is crucial for healthcare professionals to consider this risk when administering Butorphanol to clients with a history of substance use disorder. Choices A, B, and C are incorrect. Butorphanol is less likely to be abused than morphine, causes less respiratory depression than morphine, and can be reversed with an opioid antagonist.
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