ATI RN
ATI Pharmacology Test Bank
1. A client has a new prescription for Methotrexate to treat Rheumatoid Arthritis. Which of the following instructions should the nurse provide?
- A. Take this medication with food to prevent nausea.
- B. Drink plenty of fluids to stay hydrated while on this medication.
- C. Avoid alcohol while taking this medication.
- D. Wear sunscreen when outdoors while taking this medication.
Correct answer: C
Rationale: The correct instruction for a client taking Methotrexate is to avoid alcohol, as it can increase the risk of liver damage. Alcohol consumption should be avoided to prevent potential adverse effects while on this medication.
2. A client has a new prescription for nitroglycerin transdermal patches. Which of the following instructions should the nurse include?
- A. Apply the patch to a different location each day.
- B. Remove the patch every night before bedtime.
- C. Massage the patch area gently after application.
- D. Shave the area before applying the patch.
Correct answer: B
Rationale: The correct instruction for a client using nitroglycerin transdermal patches is to remove the patch every night before bedtime. This practice helps prevent tolerance to the medication's effects. Continuous exposure to nitroglycerin can result in the body becoming less responsive to its therapeutic effects over time, reducing its efficacy in managing the prescribed condition. Choices A, C, and D are incorrect. Applying the patch to a different location each day does not address the issue of tolerance. Massaging the patch area gently after application is not recommended as it may alter drug absorption. Shaving the area before applying the patch is unnecessary and may increase the risk of skin irritation.
3. Which medication is contraindicated with Nitroglycerin?
- A. Hydrochloroquine
- B. Methylprednisolone
- C. Phenazopyridine
- D. Erectile dysfunction drugs
Correct answer: D
Rationale: The correct answer is D: Erectile dysfunction drugs. Erectile dysfunction drugs are contraindicated with Nitroglycerin because they can potentiate the hypotensive effects of Nitroglycerin, leading to severe hypotension. Choices A, B, and C are incorrect because they are not known to have significant interactions with Nitroglycerin.
4. A nurse is assessing a client who is receiving IV vancomycin. The nurse notes a flushing of the neck and tachycardia. Which of the following actions should the nurse take?
- A. Document that the client experienced an anaphylactic reaction to the medication.
- B. Change the IV infusion site.
- C. Decrease the infusion rate on the IV.
- D. Apply cold compresses to the neck area.
Correct answer: C
Rationale: Flushing and tachycardia are signs of Red Man Syndrome, which can be mitigated by decreasing the infusion rate.
5. A client is receiving treatment with methotrexate. Which of the following supplements should the nurse instruct the client to take?
- A. Folic acid
- B. Vitamin D
- C. Calcium
- D. Iron
Correct answer: A
Rationale: The nurse should instruct the client to take folic acid when receiving treatment with methotrexate to reduce the risk of methotrexate toxicity. Methotrexate acts as a folic acid antagonist, leading to folic acid deficiency, which can be counteracted by supplementing with folic acid. Vitamin D, calcium, and iron are not specifically recommended to counteract methotrexate effects and do not play a significant role in mitigating methotrexate toxicity.
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