ATI RN
ATI Pharmacology
1. A client is being taught about a new prescription for Celecoxib. Which of the following information should be included in the teaching?
- A. Increases the risk for a myocardial infarction
- B. Decreases the risk of stroke
- C. Inhibits COX-1
- D. Increases platelet aggregation
Correct answer: A
Rationale: The correct answer is A: 'Increases the risk for a myocardial infarction.' Celecoxib, a COX-2 inhibitor, increases the risk for a myocardial infarction due to its effect on suppressing vasodilation, which can lead to this adverse cardiovascular event. Choices B, C, and D are incorrect. Celecoxib does not decrease the risk of stroke, inhibit COX-1, or increase platelet aggregation. It's crucial for the nurse to educate the client about the increased risk for a myocardial infarction when taking Celecoxib and emphasize monitoring for signs of heart issues and the importance of seeking prompt medical attention if symptoms occur.
2. A client has a new prescription for Ranitidine to treat peptic ulcer disease. Which of the following instructions should the nurse include?
- A. Take the medication on an empty stomach.
- B. Avoid smoking while taking this medication.
- C. Increase intake of dairy products.
- D. Expect a yellow tinge to the skin.
Correct answer: B
Rationale: The correct instruction that the nurse should include for a client prescribed Ranitidine to treat peptic ulcer disease is to avoid smoking while taking the medication. Smoking can interfere with the effectiveness of ranitidine and worsen ulcer symptoms. Therefore, it is crucial for clients to abstain from smoking to ensure optimal therapeutic outcomes. Choices A, C, and D are incorrect. Taking Ranitidine with or without food does not significantly affect its effectiveness, there is no specific need to increase intake of dairy products, and expecting a yellow tinge to the skin is not a common side effect associated with Ranitidine.
3. During the repair of a skin laceration, a client receives a local anesthetic of Lidocaine. For which of the following adverse reactions should the nurse monitor the client?
- A. Seizures
- B. Tachycardia
- C. Hypertension
- D. Fever
Correct answer: A
Rationale: Seizures are a potential adverse reaction following the administration of local anesthetics like Lidocaine. This adverse effect is important to monitor as it can be life-threatening and requires immediate intervention. It is crucial for the nurse to be vigilant in recognizing any signs of seizure activity to ensure the client's safety and well-being.
4. A healthcare professional is preparing to administer a transfusion of 300 mL of pooled platelets for a client with severe Thrombocytopenia. How should the healthcare professional plan to administer the transfusion over which of the following time frames?
- A. Within 30 minutes/unit
- B. Within 60 minutes/unit
- C. Within 2 hours/unit
- D. Within 4 hours/unit
Correct answer: A
Rationale: Platelets are fragile components that must be administered promptly to minimize the risk of clumping. The correct administration time for platelets is within 15 to 30 minutes per unit to maintain their therapeutic effectiveness and reduce adverse effects. Administering platelets over longer time frames can lead to decreased efficacy and potential harm to the patient. Therefore, the correct answer is to administer the 300 mL of pooled platelets within 30 minutes per unit.
5. A nurse on a medical-surgical unit administers a hypnotic medication to an older adult client at 2100. The next morning, the client is drowsy and wants to sleep instead of eating breakfast. Which of the following factors should the nurse identify as a possible reason for the client's drowsiness?
- A. Reduced cardiac function
- B. First-pass effect
- C. Reduced hepatic function
- D. Increased gastric motility
Correct answer: C
Rationale: In older adults, reduced hepatic function can lead to prolonged effects of medications metabolized by the liver. This situation can result in increased drug levels in the body, causing drowsiness and other side effects. Adjusting the dosage of the hypnotic medication may be necessary to prevent such adverse effects in older adult clients. Choice A, reduced cardiac function, is not directly related to the metabolism of the medication and is unlikely to cause drowsiness. Choice B, first-pass effect, refers to the initial metabolism of a drug in the liver before it enters circulation, but it is not the cause of drowsiness in this scenario. Choice D, increased gastric motility, does not play a significant role in the metabolism of the medication and is not a likely cause of the client's drowsiness.
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