ATI RN
ATI Pharmacology
1. A healthcare provider is reviewing the health care record of a client who is asking about conjugated equine estrogens. The provider should inform the client this medication is contraindicated in which of the following conditions?
- A. Atrophic vaginitis
- B. Dysfunctional uterine bleeding
- C. Osteoporosis
- D. Thrombophlebitis
Correct answer: D
Rationale: Conjugated equine estrogens are contraindicated in clients with a history of thrombophlebitis due to the increased risk of thrombotic events associated with estrogen use. Thrombophlebitis is characterized by inflammation of a vein with the formation of a clot, and estrogen can further exacerbate this condition, leading to serious complications. Choices A, B, and C are not contraindications for conjugated equine estrogens. Atrophic vaginitis and osteoporosis are conditions where estrogen therapy may actually be indicated. Dysfunctional uterine bleeding is another condition where estrogen therapy can be used to help regulate menstrual bleeding.
2. A nurse is teaching a client who has a new prescription for Etanercept for Rheumatoid Arthritis. Which of the following statements by the client indicates an understanding of the teaching?
- A. I will need to get my blood drawn periodically while on this medication.'
- B. I should stop taking this medication if I develop a rash.'
- C. I will need to limit my alcohol intake to no more than one drink per week.'
- D. I should self-administer this medication subcutaneously into the muscle.'
Correct answer: A
Rationale: Etanercept can cause bone marrow suppression, so it is important to monitor blood counts regularly.
3. What is a serious adverse reaction to penicillin?
- A. Liver Failure
- B. Anaphylaxis
- C. Respiratory Depression
- D. Edema
Correct answer: B
Rationale: The correct answer is B: Anaphylaxis. Anaphylaxis is a severe allergic reaction that can occur as a serious adverse reaction to penicillin. It is a life-threatening condition that requires immediate medical attention. Choices A, C, and D are incorrect. Liver failure is not a typical adverse reaction to penicillin, respiratory depression is more commonly associated with opioid medications, and edema is not a common severe adverse reaction to penicillin.
4. Which of the following is classified as a class IA Sodium Channel blocker?
- A. Quinidine
- B. Disopyramide
- C. Aminodarone
- D. Propafenone
Correct answer: A
Rationale: Quinidine is classified as a class IA sodium channel blocker. Class IA antiarrhythmics, like quinidine, work by blocking sodium channels and delaying repolarization. Propafenone, mentioned in the original rationale, is actually a class IC antiarrhythmic agent, not a class IA sodium channel blocker.
5. A client has a new prescription for Atorvastatin. Which of the following instructions should be included?
- A. Take this medication with food.
- B. Avoid drinking grapefruit juice.
- C. Take this medication in the morning.
- D. Increase your intake of potassium-rich foods.
Correct answer: B
Rationale: The correct answer is to avoid drinking grapefruit juice when taking Atorvastatin. Grapefruit juice can interfere with the metabolism of Atorvastatin, leading to increased blood levels of the medication, which can result in a higher risk of adverse effects, such as muscle pain and liver damage. It is important for the client to follow this instruction to ensure the safe and effective use of Atorvastatin. Choices A, C, and D are incorrect. While taking Atorvastatin with food may be recommended for some individuals to reduce stomach upset, it is not a crucial instruction. The timing of Atorvastatin administration can vary depending on individual needs and is not universally fixed to the morning. Increasing potassium-rich foods is not directly related to Atorvastatin use and is not a standard precautionary measure associated with this medication.
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