a nurse is caring for four clients who have peptic ulcer disease the nurse should recognize misoprostol is contraindicated for which of the following

ATI RN

ATI Pharmacology Proctored Exam

1. A healthcare professional is caring for four clients who have Peptic Ulcer Disease. The healthcare professional should recognize Misoprostol is contraindicated for which of the following clients?

A. A client who is pregnant
B. A client who has osteoarthritis
C. A client who has a kidney stone
D. A client who has a urinary tract infection

Correct answer: A

Rationale: Misoprostol is contraindicated in pregnancy as it can induce labor and potentially lead to harm to the fetus. Therefore, it should not be used in pregnant clients due to its uterotonic effects. For clients with osteoarthritis, kidney stone, or urinary tract infection, Misoprostol is not contraindicated specifically for these conditions.

2. A client is being discharged with a new prescription for Clopidogrel. Which of the following instructions should the nurse include?

A. Avoid taking aspirin while on this medication.
B. Take this medication with food.
C. Avoid eating foods high in potassium.
D. Take this medication at bedtime.

Correct answer: A

Rationale: The correct instruction for a client prescribed Clopidogrel is to avoid taking aspirin while on this medication. Clopidogrel is an antiplatelet medication that can increase the risk of bleeding. Aspirin and other NSAIDs can potentiate the risk of bleeding, so they should be avoided while taking Clopidogrel to prevent adverse effects. Choices B, C, and D are incorrect because Clopidogrel does not need to be taken with food, there is no specific dietary restriction related to potassium, and the timing of administration (bedtime) is not a critical instruction for this medication.

3. A client has a new prescription for hydrochlorothiazide to treat hypertension. Which of the following instructions should be included?

A. Take the medication in the morning.
B. Increase intake of potassium-rich foods.
C. Avoid sun exposure while taking this medication.
D. Limit fluid intake to 1 liter per day.

Correct answer: B

Rationale: The correct instruction that should be included for a client prescribed hydrochlorothiazide is to increase the intake of potassium-rich foods. Hydrochlorothiazide, being a diuretic, can lead to hypokalemia by enhancing potassium excretion. Increasing consumption of potassium-rich foods like bananas or oranges can help prevent hypokalemia and maintain electrolyte balance. Choices A, C, and D are incorrect. Taking the medication in the morning is not a specific instruction related to hydrochlorothiazide. Avoiding sun exposure is more relevant for photosensitive medications, not hydrochlorothiazide. Limiting fluid intake to 1 liter per day is not necessary unless specifically advised by a healthcare provider.

4. Which of the following drugs is associated with the reaction of Cinchonism?

A. Valproic acid
B. Quinidine
C. Isoniazid
D. Ethosuximide

Correct answer: B

Rationale: Cinchonism is associated with Quinidine, not Valproic acid, Isoniazid, or Ethosuximide. Cinchonism is characterized by symptoms such as tinnitus, dizziness, and headaches. Quinidine, being an antiarrhythmic agent, can lead to this condition as a side effect.

5. In which of the following cases is Lansoprazole not used?

A. Gastritis
B. Peptic Ulcers
C. Zollinger-Ellison syndrome
D. Thalamus hypertrophy

Correct answer: D

Rationale: Lansoprazole is a proton pump inhibitor mainly used to treat conditions related to the stomach, such as gastritis, peptic ulcers, and Zollinger-Ellison syndrome. Thalamus hypertrophy is not a condition that Lansoprazole is indicated for; it is used for gastrointestinal issues and not neurological conditions.