ATI RN
ATI Pharmacology
1. A client is receiving heparin therapy. Which laboratory value should be monitored by the nurse to evaluate the effectiveness of the therapy?
- A. PT
- B. aPTT
- C. INR
- D. Platelet count
Correct answer: B
Rationale: The activated partial thromboplastin time (aPTT) is specifically used to monitor the effectiveness of heparin therapy. It should be maintained at 1.5 to 2 times the normal level. Monitoring aPTT helps ensure that the therapeutic range of heparin is achieved to prevent clot formation while minimizing the risk of bleeding complications. Choice A (PT) is incorrect as it is used to monitor warfarin therapy, not heparin. Choice C (INR) is also incorrect as it is primarily used to monitor warfarin therapy. Choice D (Platelet count) is not directly related to monitoring the effectiveness of heparin therapy.
2. A healthcare professional is preparing to administer Enoxaparin to a client. Which of the following actions should the healthcare professional take?
- A. Administer the medication orally.
- B. Massage the injection site after administration.
- C. Insert the needle at a 45- to 90-degree angle.
- D. Aspirate before injecting the medication.
Correct answer: C
Rationale: Enoxaparin should be administered subcutaneously at a 45- to 90-degree angle. This angle ensures proper delivery of the medication. Massaging the injection site should be avoided to prevent bruising and possible tissue damage. Aspiration is not required for subcutaneous injections like Enoxaparin. Therefore, the correct action for administering Enoxaparin is to insert the needle at a 45- to 90-degree angle.
3. A client has a prescription for Furosemide. Which of the following instructions should the nurse include?
- A. Take the medication in the morning.
- B. Increase your intake of potassium-rich foods.
- C. Expect your urine to turn orange.
- D. Avoid prolonged sunlight exposure.
Correct answer: B
Rationale: The correct answer is B: 'Increase your intake of potassium-rich foods.' Furosemide is a loop diuretic that can lead to hypokalemia (low potassium levels) due to increased excretion of potassium in the urine. To counteract this effect and maintain electrolyte balance, the client should be advised to increase their intake of potassium-rich foods. This instruction helps prevent potential complications associated with low potassium levels. Choices A, C, and D are incorrect. Taking Furosemide in the morning does not affect its effectiveness; urine turning orange is not an expected side effect of Furosemide; and avoiding prolonged sunlight exposure is not directly related to Furosemide use.
4. What is the primary use of lithium?
- A. Lower blood glucose
- B. Slow the heart rate
- C. Stabilize mood
- D. Heal ulcers
Correct answer: C
Rationale: The correct answer is C: Stabilize mood. Lithium is primarily used to stabilize mood, especially in conditions like bipolar disorder. It helps in reducing the frequency and severity of manic episodes, making it an essential medication for mood stabilization. Choices A, B, and D are incorrect as lithium is not used to lower blood glucose, slow the heart rate, or heal ulcers.
5. A client with angina asks about obtaining a prescription for sildenafil to treat erectile dysfunction. Which of the following medications is contraindicated with Sildenafil?
- A. Aspirin
- B. Isosorbide
- C. Clopidogrel
- D. Atorvastatin
Correct answer: B
Rationale: Isosorbide is an organic nitrate used to manage angina. Concurrent use of sildenafil with organic nitrates, like isosorbide, is contraindicated due to the risk of fatal hypotension. It is essential for clients to avoid taking nitrate medications within 24 hours of using isosorbide to prevent serious complications.
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