ATI RN
ATI Pharmacology Proctored Exam
1. A client is admitted for a surgical procedure. Which of the following preexisting conditions can be a contraindication for the use of Ketamine as an intravenous anesthetic?
- A. Peptic ulcer disease
- B. Breast cancer
- C. Diabetes mellitus
- D. Schizophrenia
Correct answer: D
Rationale: Ketamine is known to produce psychological effects, such as hallucinations. Therefore, individuals with schizophrenia are at increased risk of experiencing exacerbation of their symptoms if given Ketamine, making it a contraindication for its use as an intravenous anesthetic. Peptic ulcer disease, breast cancer, and diabetes mellitus are not contraindications for Ketamine use as an intravenous anesthetic.
2. Which drug class has been found to decrease mortality if given within 8 hours of an MI due to a decrease in cardiac workload?
- A. Antiplatelets
- B. Beta-adrenergic blockers
- C. ACE inhibitors
- D. Calcium channel blockers
Correct answer: B
Rationale: Beta-adrenergic blockers have been shown to decrease mortality when administered within 8 hours of a myocardial infarction (MI). They do so by reducing cardiac workload, which helps improve outcomes post-MI. These drugs work by blocking the effects of adrenaline on the heart, leading to decreased heart rate, blood pressure, and myocardial oxygen demand, thereby protecting the heart muscle from further damage. This makes them a crucial part of the treatment regimen for acute coronary syndromes like MI.
3. Which of the following is a potassium-sparing diuretic?
- A. Furosemide
- B. Spironolactone
- C. Hydrochlorothiazide
- D. Bumetanide
Correct answer: B
Rationale: Spironolactone is classified as a potassium-sparing diuretic. It works by antagonizing the aldosterone receptor, leading to potassium retention and sodium excretion. This mechanism makes it a suitable choice for conditions where potassium retention is desired, such as in patients with heart failure or liver cirrhosis. Choices A, C, and D are not potassium-sparing diuretics. Furosemide, hydrochlorothiazide, and bumetanide are loop diuretics and thiazide diuretics, respectively, which promote the excretion of potassium.
4. A client has a new prescription for Ramelteon and is receiving teaching from a nurse. The nurse should instruct the client to avoid which of the following foods while taking this medication?
- A. Baked potato
- B. Fried chicken
- C. Whole-grain bread
- D. Citrus fruits
Correct answer: B
Rationale: The correct answer is B: Fried chicken. High-fat foods like fried chicken can prolong the absorption of Ramelteon, potentially reducing its effectiveness. It is important to avoid such foods to ensure the medication works as intended.
5. What is the primary use of lithium?
- A. Lower blood glucose
- B. Slow the heart rate
- C. Stabilize mood
- D. Heal ulcers
Correct answer: C
Rationale: The correct answer is C: Stabilize mood. Lithium is primarily used to stabilize mood, especially in conditions like bipolar disorder. It helps in reducing the frequency and severity of manic episodes, making it an essential medication for mood stabilization. Choices A, B, and D are incorrect as lithium is not used to lower blood glucose, slow the heart rate, or heal ulcers.
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