ATI RN
ATI Pharmacology Quizlet
1. A client with HIV is beginning therapy with zidovudine. The nurse should monitor the client for which of the following adverse effects of this medication?
- A. Fatigue
- B. Blurred vision
- C. Ringing in the ears
- D. Constipation
Correct answer: A
Rationale: Fatigue is a common adverse effect of zidovudine due to its impact on bone marrow, leading to anemia. Zidovudine is known to suppress bone marrow function, resulting in decreased production of red blood cells and subsequently causing fatigue due to anemia. Monitoring for fatigue is essential to ensure early detection and management of this adverse effect.
2. A client receiving chemotherapy with Methotrexate asks why Leucovorin is being given. Which of the following responses should the nurse use?
- A. Leucovorin reduces the risk of a transfusion reaction from Methotrexate.
- B. Leucovorin increases platelet production and prevents bleeding.
- C. Leucovorin potentiates the cytotoxic effects of Methotrexate.
- D. Leucovorin protects healthy cells from Methotrexate's toxic effects.
Correct answer: D
Rationale: Leucovorin, a folic acid derivative and an antagonist to Methotrexate, is given within 12 hours of high doses of Methotrexate to protect healthy cells from the toxic effects of Methotrexate. It helps to reduce the bone marrow suppression and gastrointestinal side effects caused by Methotrexate, supporting the client's overall well-being during chemotherapy treatment. Choices A, B, and C are incorrect because Leucovorin does not reduce the risk of a transfusion reaction from Methotrexate, increase platelet production, prevent bleeding, or potentiate the cytotoxic effects of Methotrexate. Instead, Leucovorin works by rescuing healthy cells from the toxic effects of Methotrexate.
3. A client is taking Furosemide for heart failure. Which of the following laboratory tests should the nurse monitor to assess for an adverse effect of this medication?
- A. Serum potassium.
- B. Serum calcium.
- C. Serum sodium.
- D. Serum magnesium.
Correct answer: A
Rationale: Furosemide, a loop diuretic commonly used in heart failure, can cause hypokalemia (low potassium levels) as a side effect. Monitoring serum potassium levels is crucial to detect and prevent complications associated with low potassium levels, such as cardiac arrhythmias. Therefore, the nurse should prioritize assessing the client's serum potassium levels regularly while on Furosemide. Serum calcium, sodium, and magnesium levels are not typically affected by Furosemide and are not the primary focus of monitoring for adverse effects of this medication.
4. A client has a new prescription for allopurinol. Which of the following instructions should the nurse include?
- A. Drink 2 liters of water daily.
- B. Avoid taking the medication on an empty stomach.
- C. Limit vitamin C intake while taking this medication.
- D. Take an iron supplement while on this medication.
Correct answer: A
Rationale: The correct instruction for a client prescribed allopurinol is to drink 2 liters of water daily. This helps reduce the risk of kidney stones, a potential side effect of allopurinol use. Adequate hydration is essential to prevent kidney stone formation and maintain kidney function while taking this medication.
5. A nurse is providing instructions to a client who has a prescription for Amoxicillin and Clarithromycin to treat a Peptic Ulcer. Which of the following information should the nurse include in the teaching?
- A. Take these medications with foo '
- B. These medications can turn your stool black.'
- C. These medications can cause photosensitivity.'
- D. The purpose of these medications is to decrease the pH of gastric juices in the stomach.'
Correct answer: A
Rationale: The nurse should instruct the client to take these medications with food to reduce GI disturbances.
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