ATI RN
ATI Pathophysiology Test Bank
1. What is responsible for initiating clonal selection?
- A. B cells
- B. T cells
- C. Antigens
- D. Lymphocytes
Correct answer: C
Rationale: Antigens are the correct answer as they are the molecules that trigger the immune response by binding to specific B or T cells. This binding activates these cells, leading to their proliferation and differentiation to fight off the antigen. B cells and T cells are the responders to antigens, not the initiators of clonal selection. Lymphocytes is a broad term encompassing both B and T cells, so it is not the specific factor responsible for initiating clonal selection.
2. Which of the following wounds is most likely to heal by secondary intention?
- A. A finger laceration received while cutting onions
- B. A stage IV pressure ulcer that developed in a nursing home
- C. A needlestick injury received while administering parenteral medication
- D. An incision from an open appendectomy
Correct answer: B
Rationale: A stage IV pressure ulcer is a deep wound involving tissue loss that typically heals by secondary intention. This process involves the wound healing from the bottom up with granulation tissue and often results in significant scarring. Choice A, a finger laceration, would generally heal by primary intention due to its clean edges and minimal tissue loss. Choice C, a needlestick injury, is likely to be sutured and heal by primary intention since it is a small, clean wound. Choice D, an incision from an open appendectomy, is usually closed with sutures and heals by primary intention as well.
3. Which of the following is a clinical manifestation in a patient with renal impairment associated with polycystic kidney disease?
- A. Suprapubic pain
- B. Periorbital edema
- C. Low serum creatinine level
- D. Palpable kidneys
Correct answer: D
Rationale: Palpable kidneys are a common clinical manifestation in patients with polycystic kidney disease due to the enlarged kidneys with multiple cysts. Suprapubic pain is not typically associated with this condition. Periorbital edema is more commonly seen in conditions like nephrotic syndrome. A low serum creatinine level is not a typical finding in renal impairment, as impaired kidneys usually lead to an elevated serum creatinine level.
4. A patient is prescribed testosterone gel for hypogonadism. What important instruction should the nurse provide regarding the application of this medication?
- A. Apply the gel to the chest or upper arms.
- B. Apply the gel to the face and neck.
- C. Apply the gel to the genitals for maximum absorption.
- D. Apply the gel to the scalp and back.
Correct answer: A
Rationale: The correct answer is to apply the testosterone gel to the chest or upper arms. This is recommended to minimize the risk of unintentional transfer of the medication to others, especially women and children, through skin contact. Applying the gel to the face, neck, or genitals is not advised as it can lead to unintended exposure to others. Additionally, applying the gel to the scalp or back is not appropriate as these areas are not indicated for absorption of testosterone.
5. A patient is taking medroxyprogesterone acetate (Provera) for the treatment of endometriosis. What should the nurse include in the patient teaching?
- A. Take the medication with food to prevent gastrointestinal upset.
- B. Avoid prolonged sun exposure while taking this medication.
- C. Take the medication at the same time each day to maintain consistent hormone levels.
- D. Discontinue the medication if side effects occur.
Correct answer: C
Rationale: The correct answer is to take the medication at the same time each day to maintain consistent hormone levels. This is important for the effectiveness of medroxyprogesterone acetate. Choice A is incorrect because medroxyprogesterone acetate does not need to be taken with food. Choice B is irrelevant as sun exposure is not a concern with this medication. Choice D is incorrect as discontinuing the medication without consulting a healthcare provider can lead to adverse effects.
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