Nursing Elites

1. Like longitudinal research, cross-sectional studies can be threatened by __________.

• A. practice effects
• B. participant dropout
• C. sequential timing
• D. cohort effects

Correct answer: D

Rationale: Cross-sectional studies can be threatened by cohort effects because different age groups may have experienced different historical or social contexts, influencing the results. This disparity can lead to invalid comparisons between age groups, confounding the study's findings. Option A, practice effects, refer to changes in participants' behavior due to repeated testing, not a specific threat to cross-sectional studies. Participant dropout (Option B) is a threat related to attrition in longitudinal studies, not cross-sectional studies. Sequential timing (Option C) does not pose a threat to cross-sectional studies; instead, it refers to the order of tasks in a study design.

2. __________ increases tenfold from the twentieth week until birth.

• A. Amniotic fluid
• B. Brain weight
• C. Fetal length
• D. Neuron production

Correct answer: B

Rationale: Brain weight increases tenfold from the twentieth week until birth. This rapid growth and development of the brain during the prenatal period is crucial for setting the foundation for future cognitive and neurological functions. Choices A, C, and D are incorrect because although they also undergo changes during prenatal development, none of them increase tenfold from the twentieth week until birth, unlike brain weight.

3. In the information-processing system, where does information first enter?

• A. central executive
• B. short-term memory store
• C. sensory register
• D. long-term memory store

Correct answer: C

Rationale: In the information-processing system, information first enters the sensory register. This is where sensory information from the environment is briefly stored before being processed further. The central executive is responsible for coordinating cognitive processes, the short-term memory store holds information temporarily for immediate tasks, and the long-term memory store stores information for long periods, but the sensory register is the initial entry point for incoming information.

4. Dr. O'Connor wants 90-year-old Mr. Takashi to participate in a research study that involves moderate risks. Mr. Takashi is incapable of consenting. Which statement best expresses your advice regarding Mr. Takashi's participation in the study?

• A. He should not be allowed to participate in the study under any circumstances.
• B. He should be allowed to participate in the study regardless of the benefit.
• C. He should be allowed to participate in the study only if his participation will benefit others.
• D. He should be allowed to participate in the study only if it is likely to benefit him directly.

Correct answer: D

Rationale: Mr. Takashi should be allowed to participate in the study only if it is likely to benefit him directly. This decision aligns with the principle of beneficence in research ethics, which emphasizes maximizing benefits and minimizing risks for research participants. Since Mr. Takashi is incapable of giving consent, his participation should be based on the likelihood of direct benefits to him rather than solely for the benefit of others or solely for research purposes. Option A is too restrictive and does not consider potential benefits to Mr. Takashi. Option B is flawed as it disregards the need for the study to benefit Mr. Takashi. Option C focuses on benefiting others, which is not the primary consideration when the participant cannot give consent.

5. Currently, the most widely used potent teratogen is __________.

• A. aspirin
• B. diethylstilbestrol (DES)
• C. thalidomide
• D. isotretinoin

Correct answer: D

Rationale: The correct answer is D, isotretinoin. Isotretinoin is a medication commonly used to treat severe acne, but it is a potent teratogen, meaning it can cause severe birth defects if taken during pregnancy. Aspirin (choice A) is not a widely used potent teratogen. Diethylstilbestrol (DES) (choice B) was a known teratogen, but it is not currently widely used. Thalidomide (choice C) was another historical teratogen, but it is also not currently widely used. Therefore, isotretinoin is the most relevant answer as it is a commonly used medication that poses a high risk of birth defects if used during pregnancy.

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