a nurse is caring for a client who is prescribed metformin which of the following laboratory values should the nurse monitor to assess for potential a

ATI RN

ATI Pharmacology

1. A client is prescribed Metformin. Which of the following laboratory values should be monitored to assess for potential adverse effects?

A. Blood glucose
B. Creatine kinase
C. Hemoglobin A1c
D. Serum creatinine

Correct answer: D

Rationale: The correct answer is D: Serum creatinine. Metformin can potentially cause lactic acidosis, particularly in patients with impaired renal function. Monitoring serum creatinine levels is crucial to assess kidney function and detect any adverse effects of Metformin on renal health. Choices A, B, and C are incorrect as blood glucose, creatine kinase, and hemoglobin A1c levels are not directly monitored to assess for potential adverse effects of Metformin. Blood glucose monitoring is typically done to assess the efficacy of antidiabetic medications like Metformin, while creatine kinase levels are indicative of muscle damage and hemoglobin A1c reflects long-term blood sugar control.

2. A client has a new prescription for Hydrochlorothiazide. Which of the following information should the nurse include?

A. Take the medication with food.
B. Plan to take the medication at bedtime.
C. Expect increased swelling of the ankles.
D. Limit fluid intake in the morning.

Correct answer: A

Rationale: When educating a client about taking Hydrochlorothiazide, the nurse should advise taking the medication with food or after meals to prevent gastrointestinal upset. This medication is a diuretic, so it is important to maintain adequate fluid intake throughout the day to prevent dehydration. Taking it at bedtime is not necessary, and increased swelling of the ankles is not an expected side effect of this medication. Limiting fluid intake in the morning is not necessary and could lead to dehydration, which is a potential side effect of this diuretic.

3. Which of the following is NOT an opioid or NSAID?

A. Morphine
B. Ibuprofen
C. Hydromorphone
D. Acetaminophen

Correct answer: D

Rationale: Acetaminophen is the correct answer as it is not classified as an opioid or NSAID. Acetaminophen is considered a non-opioid analgesic, which means it works by a different mechanism than opioids and NSAIDs to relieve pain and reduce fever. Morphine, hydromorphone, and ibuprofen, on the other hand, are classified as opioids or NSAIDs. Morphine and hydromorphone are opioids, while ibuprofen is an NSAID (Nonsteroidal Anti-Inflammatory Drug), all of which work through different mechanisms compared to acetaminophen.

4. Which of the following is not a known effect of the drug Clozapine?

A. Agranulocytosis
B. Antipsychotic
C. Used for Schizophrenia
D. Hyperactivity

Correct answer: D

Rationale: Clozapine is associated with side effects like agranulocytosis (a serious blood condition), sedation (not hyperactivity), and is used as an antipsychotic to treat schizophrenia. Hyperactivity is not a typical effect of Clozapine, making it the correct answer in this context.

5. A healthcare professional is preparing to administer a dose of Hydromorphone IV to a client. Which of the following actions should the healthcare professional take?

A. Administer the medication over 5 minutes.
B. Administer a dose of Naloxone prior to giving the Hydromorphone.
C. Assess the client's blood pressure prior to administration.
D. Inject the medication into the client's subcutaneous tissue.

Correct answer: A

Rationale: The correct action for the healthcare professional preparing to administer IV Hydromorphone to a client is to administer the medication over 5 minutes. This slow administration is crucial to reduce the risk of hypotension and respiratory depression. Administering the medication rapidly can lead to adverse effects. Option B, administering Naloxone prior to Hydromorphone, is incorrect because Naloxone is used as an antidote for opioid overdose, not as a routine pre-medication. Option C, assessing the client's blood pressure before administration, is important but not the immediate action to take to reduce adverse effects of Hydromorphone. Option D, injecting the medication into the client's subcutaneous tissue, is incorrect as Hydromorphone is meant for intravenous administration for rapid onset of action.