the probability of having a child with downs syndrome increases with the age of the parents
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HESI Maternal Newborn

1. Does the probability of having a child with Down’s syndrome increase with the age of the parents?

Correct answer: A

Rationale: The correct answer is A: TRUE. Advanced parental age, particularly maternal age, is associated with an increased risk of Down's syndrome in offspring. As parents get older, the likelihood of having a child with Down's syndrome increases. Choices B, C, and D are incorrect because the risk of Down's syndrome is known to rise with parental age, especially maternal age, due to the increased likelihood of chromosomal abnormalities during egg formation.

2. According to a study in 2014 by Skakkebaek et al., who among the following is most likely to have gynecomastia?

Correct answer: C

Rationale: Individuals with Klinefelter syndrome have an extra X chromosome (XXY) and typically have reduced testosterone levels, which can lead to gynecomastia (enlarged breasts). This condition is not usually associated with Down syndrome (choice A), XYY syndrome (choice B), or Turner syndrome (choice D), making them less likely to have gynecomastia.

3. Which of the following statements is true of a sperm cell?

Correct answer: D

Rationale: The correct answer is D. A sperm cell is indeed one of the smallest cells in the human body, much smaller than an egg cell. Choice A is incorrect as sperm cells are much smaller than egg cells. Choice B is incorrect because a sperm cell carries either an X or a Y chromosome, not two Y chromosomes. Choice C is incorrect since sperm cells move in a purposeful manner guided by various factors within a woman's reproductive tract, not randomly.

4. Which of the following is most likely to develop sickle cell anemia?

Correct answer: C

Rationale: Sickle cell anemia is most commonly found in individuals of African American descent. This is because sickle cell trait provides some protection against malaria, and historically, regions where malaria is or was prevalent have higher rates of sickle cell anemia. Therefore, individuals with African ancestry are at a higher risk of developing sickle cell anemia compared to other populations. Choices A, B, and D are less likely to develop sickle cell anemia due to lower genetic prevalence in their respective populations.

5. Do sebaceous glands cause a developing organism to grow arms or wings, skin, or scales?

Correct answer: B

Rationale: The correct answer is B: False. Sebaceous glands are associated with the skin's oil production and have no role in the development of limbs or body coverings. Sebaceous glands primarily produce sebum, an oily substance that lubricates and waterproofs the skin and hair. Choices A, C, and D are incorrect because sebaceous glands do not influence the growth of arms, wings, skin, or scales in a developing organism.

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