the probability of having a child with downs syndrome increases with the age of the parents
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HESI Maternal Newborn

1. Does the probability of having a child with Down’s syndrome increase with the age of the parents?

Correct answer: A

Rationale: The correct answer is A: TRUE. Advanced parental age, particularly maternal age, is associated with an increased risk of Down's syndrome in offspring. As parents get older, the likelihood of having a child with Down's syndrome increases. Choices B, C, and D are incorrect because the risk of Down's syndrome is known to rise with parental age, especially maternal age, due to the increased likelihood of chromosomal abnormalities during egg formation.

2. Is Duchenne muscular dystrophy a sex-linked abnormality?

Correct answer: A

Rationale: The correct answer is A: TRUE. Duchenne muscular dystrophy is an X-linked recessive disorder, primarily affecting males. This is due to the inheritance of the mutated gene on the X chromosome. Choices B, C, and D are incorrect because Duchenne muscular dystrophy is specifically classified as a sex-linked disorder affecting males due to the inheritance pattern.

3. How many chromosomes are typically found in human cells, organized into pairs?

Correct answer: B

Rationale: Human cells typically contain 46 chromosomes organized into 23 pairs. This is the correct number for a normal human cell. Choices A, C, and D are incorrect because they do not represent the typical chromosome count in human cells.

4. Which neonatal complications are associated with hypertension in the mother?

Correct answer: A

Rationale: Neonatal complications associated with maternal hypertension are primarily due to placental insufficiency. The correct answer is A, which includes Intrauterine Growth Restriction (IUGR) and prematurity. These complications arise from inadequate blood flow to the fetus, leading to growth restriction and premature birth. Choices B, seizures, and cerebral hemorrhage are more commonly maternal complications rather than neonatal ones. Choice C, hepatic or renal dysfunction, pertains to maternal complications of hypertensive disorders in pregnancy, not neonatal issues. Choice D, placental abruption, and Disseminated Intravascular Coagulation (DIC) are conditions linked to maternal morbidity and mortality, not neonatal complications.

5. After mitosis, the genetic code is identical in new cells unless _________ occur through radiation or other environmental influences.

Correct answer: D

Rationale: After mitosis, the genetic code is typically preserved and remains identical in the new cells. However, mutations can occur due to radiation or environmental influences, leading to changes in the DNA sequence and potentially altering the genetic code. Therefore, the correct answer is 'mutations.' Choices A, B, and C are incorrect because reductions, expulsions, and conceptions do not accurately describe the changes in the genetic code that can result from external factors. Mutations are the only option that reflects the alteration in the genetic code caused by external influences, making it the correct choice in this context.

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