Nursing Elites

1. A client with severe rheumatoid arthritis is prescribed methotrexate. The nurse should monitor the client for which potential adverse effect?

• A. Bone marrow suppression
• B. Increased risk of infection
• C. Liver toxicity
• D. Kidney stones

Correct answer: A

Rationale: The correct answer is A: Bone marrow suppression. Methotrexate, commonly used in rheumatoid arthritis, can lead to bone marrow suppression, reducing the production of blood cells and increasing the risk of infection. Monitoring for signs of anemia, leukopenia, and thrombocytopenia is crucial to detect bone marrow suppression early and prevent complications. Choices B, C, and D are incorrect because while methotrexate can increase the risk of infection, liver toxicity, and kidney issues, the primary concern and most significant adverse effect to monitor for is bone marrow suppression due to its impact on blood cell production.

2. A client is prescribed nitroglycerin sublingual tablets. The practical nurse should reinforce which instruction?

• A. Store the tablets in a cool, dry place.
• B. Take one tablet every 5 minutes until pain is relieved, up to three tablets.
• C. Swallow the tablets whole.
• D. Chew the tablets for faster relief.

Correct answer: A

Rationale: Nitroglycerin sublingual tablets are sensitive to heat and moisture, so they should be stored in a cool, dry place to maintain their efficacy. Storing them in a cool, dry place helps prevent degradation of the medication. Choice B is incorrect because nitroglycerin tablets should be taken as directed by the healthcare provider to avoid potential overdose or adverse effects. Choice C is incorrect because sublingual tablets should be placed under the tongue to dissolve and be absorbed, not swallowed, to ensure their quick action. Choice D is incorrect because sublingual tablets should not be chewed; they are meant to be absorbed through the tissues under the tongue, and chewing them may alter their effectiveness.

3. A client with a history of myocardial infarction is prescribed atorvastatin. The nurse should monitor the client for which potential adverse effect?

• A. Liver damage
• B. Kidney damage
• C. Muscle pain
• D. Increased appetite

Correct answer: C

Rationale: The correct answer is C: Muscle pain. Atorvastatin can cause muscle pain, which may indicate rhabdomyolysis, a serious adverse effect. Rhabdomyolysis is a condition where muscle breakdown releases a protein (myoglobin) into the bloodstream, potentially leading to kidney damage. Liver damage (choice A) is a less common side effect of atorvastatin compared to muscle pain. Kidney damage (choice B) is not a direct adverse effect of atorvastatin but can occur indirectly if rhabdomyolysis is severe. Increased appetite (choice D) is not a known adverse effect of atorvastatin.

4. The nurse is studying antacids that contain magnesium and calcium for the pharmacology exam. The student nurse remembers that these antacids should be used with caution in patients with which condition?

• A. Hypertension
• B. Renal failure
• C. Heart failure
• D. Peptic ulcer disease

Correct answer: B

Rationale: Magnesium and calcium can accumulate in patients with renal failure, leading to toxicity.

5. A client with diabetes mellitus type 2 is prescribed pioglitazone. What instruction should the nurse include in the client's teaching plan?

• A. Report any signs of heart failure.
• B. Take this medication with meals.
• C. Avoid alcohol while taking this medication.
• D. Report any signs of bladder cancer.

Correct answer: A

Rationale: The correct answer is to instruct the client to report any signs of heart failure when taking pioglitazone. Pioglitazone is known to potentially exacerbate heart failure, so it is crucial for clients to monitor and report any symptoms of heart failure promptly to their healthcare provider for appropriate management. Choices B and C are important but not specific to pioglitazone use. Choice D is incorrect as bladder cancer is not a known side effect of pioglitazone.

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