HESI LPN
HESI Practice Test Pharmacology
1. A client with rheumatoid arthritis is prescribed methotrexate. The nurse should monitor for which common side effect of this medication?
- A. Liver toxicity
- B. Skin rash
- C. Hair loss
- D. Abdominal pain
Correct answer: A
Rationale: The correct answer is A: Liver toxicity. Methotrexate is known to cause liver toxicity, making regular monitoring of liver function essential. Monitoring liver function tests helps detect any signs of liver damage early, allowing for appropriate interventions to be implemented promptly.
2. What information should the practical nurse provide to a female client who started taking an oral sulfonamide for a urinary tract infection the previous day and reports slight anorexia, while also experiencing urinary frequency?
- A. Take the medication with an antacid instead of cranberry juice to reduce the anorexia.
- B. Continue to take the medication with a sip of cranberry juice, restricting fluids until the frequency is controlled.
- C. Continue to drink cranberry juice, but take the medicine on an empty stomach with a full glass of water.
- D. Take the medication with a spoonful of ice cream or applesauce and avoid drinking cranberry juice.
Correct answer: C
Rationale: The practical nurse should advise the client to take sulfonamides with a full glass of water to help prevent crystalluria. It is essential to take the medication on an empty stomach, ideally 1 hour before eating or 2 hours after eating to maximize its absorption and effectiveness. Continuing to drink cranberry juice is beneficial, but it is important to take the medicine separately to enhance its therapeutic action.
3. The healthcare professional is preparing client teaching materials on commonly used medications. Which client is most likely to benefit from a client education package about simvastatin?
- A. A 50-year-old male with a history of angina
- B. A 75-year-old male with bone cancer
- C. An 18-year-old pregnant female with diabetes
- D. A 40-year-old female with frequent vaginal infections
Correct answer: A
Rationale: Simvastatin is a medication used to lower cholesterol levels and prevent cardiovascular diseases. It is commonly prescribed for individuals at risk of heart-related conditions. Angina is a symptom of underlying heart disease, and individuals with this condition would benefit most from simvastatin to help manage their cholesterol levels and reduce the risk of cardiovascular events. Therefore, the 50-year-old male with a history of angina is the most suitable candidate for client education regarding simvastatin. Choices B, C, and D are not the most appropriate candidates for simvastatin education because bone cancer, pregnancy with diabetes, and frequent vaginal infections are not conditions typically treated with simvastatin.
4. A client with a history of stroke is prescribed warfarin. The nurse should monitor for which potential side effect?
- A. Bleeding
- B. Weight gain
- C. Headache
- D. Dizziness
Correct answer: A
Rationale: The correct answer is A: Bleeding. Warfarin is an anticoagulant medication that works by thinning the blood. One of the potential side effects of warfarin is an increased risk of bleeding. It is crucial for the nurse to monitor the client for signs of bleeding, such as unusual bruising, blood in the urine or stool, or prolonged bleeding from cuts or gums. Prompt recognition and management of bleeding are essential to prevent complications. Choices B, C, and D are incorrect as weight gain, headache, and dizziness are not common side effects of warfarin. Monitoring for bleeding is a priority due to the anticoagulant properties of warfarin.
5. A client has been taking simvastatin for 3 days and calls the nurse at the clinic to report extreme muscle tenderness and pain. Which is the most appropriate action?
- A. Notify the health care provider.
- B. Review the medication with the client.
- C. Advise the client to avoid grapefruit juice.
- D. Remind the client to limit physical activity until evaluated by the health care provider.
Correct answer: A
Rationale: Extreme muscle tenderness and pain in a client taking simvastatin could indicate rhabdomyolysis, a serious condition. Promptly notifying the health care provider is crucial to evaluate and manage this potential medical emergency. Reviewing the medication with the client may not address the urgency of the situation. Advising the client to avoid grapefruit juice is not directly related to the client's current symptoms. Reminding the client to limit physical activity until evaluated by the health care provider is not appropriate as the client's symptoms should be assessed by a professional first.
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