HESI LPN
HESI Practice Test Pharmacology
1. A client with bipolar disorder is taking lithium. Which client assessment data would indicate a potential adverse effect of lithium therapy?
- A. Increased appetite
- B. Dry mouth and increased thirst
- C. Tremors and polyuria
- D. Constipation
Correct answer: B
Rationale: When assessing a client taking lithium, dry mouth and increased thirst are indicators of potential adverse effects. Lithium can lead to nephrogenic diabetes insipidus, causing polyuria and subsequent increased thirst due to impaired water reabsorption in the kidneys. Tremors can also be a sign of lithium toxicity. Monitoring and recognizing these symptoms are crucial in managing lithium therapy and preventing further complications.
2. Which assessment finding indicates that the expected outcome of administering donepezil to a client with Alzheimer's disease has been accomplished?
- A. Increased muscle strength and tone
- B. Fewer episodes of urinary incontinence
- C. Decreased confusion and improved mood
- D. Reversal of the disease process as evidenced by increased functioning
Correct answer: C
Rationale: The correct answer is C. Donepezil is a medication used for individuals with Alzheimer's disease. Its mechanism of action involves increasing acetylcholine levels by inhibiting its breakdown, which benefits cognitive function. The expected outcome of administering donepezil is a decrease in confusion and an improvement in mood due to the medication's impact on neurotransmitters. Choices A, B, and D are incorrect because donepezil does not primarily target muscle strength, urinary incontinence, or disease reversal; instead, it aims to slow down the progression of cognitive decline in Alzheimer's disease.
3. A client has been prescribed losartan. Which change in data indicates to the practical nurse (PN) that the desired effect of this medication has been achieved?
- A. Dependent edema reduced from +3 to +1.
- B. Serum HDL increased from 35 to 55 mg/dL.
- C. Pulse rate reduced from 150 to 90 beats/min.
- D. Blood pressure reduced from 160/90 to 130/80 mm Hg.
Correct answer: D
Rationale: The correct answer is D. Losartan is prescribed for the treatment of hypertension. The desired effect of losartan is to reduce blood pressure. Therefore, a reduction in blood pressure from 160/90 to 130/80 mm Hg indicates that the desired effect of the medication has been achieved. Choices A, B, and C are not specific effects of losartan and do not directly relate to the expected outcomes of this medication. Dependent edema, serum HDL levels, and pulse rate are not typically influenced by losartan, making choices A, B, and C incorrect.
4. A client is prescribed metoprolol. The nurse should monitor for which common side effect of this medication?
- A. Dizziness
- B. Fatigue
- C. Orthostatic hypotension
- D. Headache
Correct answer: A
Rationale: The correct answer is A: Dizziness. Metoprolol, a beta-blocker, can lead to dizziness as a common side effect due to its mechanism of action in reducing heart rate and blood pressure. This effect can cause a sensation of lightheadedness or unsteadiness, particularly when standing up quickly. While fatigue, orthostatic hypotension, and headache are potential side effects of metoprolol, dizziness is commonly observed and should be closely monitored by the nurse to ensure patient safety.
5. What instruction should the nurse include in the teaching plan for a client with diabetes mellitus type 2 prescribed alogliptin?
- A. Report any signs of pancreatitis to the healthcare provider.
- B. Take this medication with meals.
- C. Avoid alcohol while taking this medication.
- D. Report any signs of heart failure to the healthcare provider.
Correct answer: A
Rationale: The correct answer is A: Report any signs of pancreatitis to the healthcare provider. Alogliptin is associated with an increased risk of pancreatitis. Therefore, clients should be instructed to report any signs of pancreatitis, such as severe abdominal pain, to their healthcare provider promptly. This is essential for early detection and management of this serious adverse effect. Choices B, C, and D are incorrect because they do not address the specific side effect associated with alogliptin.
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