HESI LPN
HESI Practice Test Pharmacology
1. A client has a prescription for heparin 1,000 units IV STAT. Several pre-filled syringes of low molecular weight heparin are available in the client's medication drawer. Which action should the nurse implement?
- A. Dilute the available heparin in 250ml of normal saline solution prior to IV administration
- B. Advise the pharmacy on the need to deliver a vial of heparin to the nursing unit immediately
- C. Calculate and administer the equivalent dose of the available low molecular weight heparin
- D. Request a prescription to change the route of administration and use the available heparin
Correct answer: B
Rationale: In this scenario, the nurse should contact the pharmacy to obtain the correct heparin formulation as the prescription calls for heparin 1,000 units IV STAT. Low molecular weight heparin is not the same as unfractionated heparin, and therefore, the nurse should not administer the available low molecular weight heparin without first obtaining the correct medication. Diluting the available heparin, calculating an equivalent dose, or changing the route of administration would not address the discrepancy between the prescribed heparin and the available low molecular weight heparin.
2. The practical nurse administers lactulose to a client. Which client outcome would indicate a therapeutic response?
- A. An increase in urine output
- B. Two to three soft stools per day
- C. Absence of nausea
- D. Decreased serum potassium
Correct answer: B
Rationale: Lactulose is a type of laxative that works by preventing the absorption of ammonia in the colon, leading to increased water absorption in the stool and softening of the stool. The therapeutic response to lactulose is indicated by the passage of two to three soft stools per day, showing that the medication is effectively promoting bowel movements.
3. A client with severe depression is prescribed sertraline. Which statement by the client indicates the need for further teaching?
- A. I can stop taking this medication once I feel better.
- B. It may take 1 to 4 weeks to notice improvement in symptoms.
- C. I should avoid alcohol while taking this medication.
- D. I should take this medication in the morning with food.
Correct answer: A
Rationale: The correct answer is A. Clients should not stop taking sertraline abruptly once they feel better without consulting their healthcare provider. It is important to complete the full course of treatment as prescribed to prevent a relapse of symptoms. Stopping the medication suddenly can lead to withdrawal symptoms and may worsen the condition. Choice B is correct because sertraline may take 1 to 4 weeks to show noticeable improvement in symptoms. Choice C is correct as alcohol should be avoided while taking sertraline due to the increased risk of side effects. Choice D is also correct as taking sertraline in the morning with food can help reduce gastrointestinal side effects.
4. A client with a diagnosis of generalized anxiety disorder is prescribed sertraline. The nurse should instruct the client that this medication may have which potential side effect?
- A. Nausea
- B. Drowsiness
- C. Insomnia
- D. Headache
Correct answer: A
Rationale: The correct answer is A: Nausea. Sertraline, a selective serotonin reuptake inhibitor (SSRI), is known to commonly cause gastrointestinal side effects such as nausea. It is recommended for clients to take sertraline with food to help minimize this potential side effect. Choice B, Drowsiness, is less commonly associated with sertraline use. Insomnia, choice C, is not a typical side effect of sertraline; in fact, it may help improve sleep in some individuals. Headache, choice D, is also not a common side effect of sertraline.
5. A client arrives at the emergency department experiencing diabetic ketoacidosis (DKA). The healthcare provider prescribes an insulin intravenous drip. Which type of insulin should the nurse locate for the registered nurse to mix into the intravenous fluids?
- A. Isophane
- B. Glargine
- C. Regular
- D. Detemir
Correct answer: C
Rationale: The correct insulin type for the nurse to mix into the intravenous fluids is regular insulin. In the scenario of diabetic ketoacidosis (DKA), rapid reduction of blood glucose levels is crucial. Regular insulin has a fast onset of action, making it suitable for intravenous administration to address the high blood sugar levels seen in DKA. Isophane, Glargine, and Detemir are not appropriate choices for intravenous administration in this emergency situation as they are intermediate-acting or long-acting insulins which do not provide the rapid response needed in DKA.
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