was a drug marketed in the 1960s to pregnant women that caused birth defects such as missing or stunted limbs in infants
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HESI Maternal Newborn

1. Which drug was marketed in the 1960s to pregnant women and caused birth defects such as missing or stunted limbs in infants?

Correct answer: C

Rationale: Thalidomide is the correct answer. Thalidomide was a drug marketed in the 1960s to pregnant women as a sedative and anti-nausea medication but tragically led to severe birth defects, including limb deformities, when taken during pregnancy. Progestin (Choice A) and Estrogen (Choice B) are hormones that are not associated with causing birth defects like Thalidomide. Oxytocin (Choice D) is a hormone that plays a role in labor and breastfeeding and is not known to cause birth defects like Thalidomide.

2. A newborn is being assessed following a forceps-assisted birth. Which of the following clinical manifestations should the nurse identify as a complication of the birth method?

Correct answer: C

Rationale: Facial palsy is a known complication of forceps-assisted birth. During forceps delivery, pressure applied to the facial nerve can result in facial palsy. The newborn may present with weakness or paralysis of the facial muscles on one side. Hypoglycemia (Choice A) is not directly related to forceps-assisted birth. Polycythemia (Choice B) is a condition characterized by an increased number of red blood cells and is not typically associated with forceps delivery. Bronchopulmonary dysplasia (Choice D) is a lung condition that primarily affects premature infants who require mechanical ventilation and prolonged oxygen therapy, not a direct outcome of forceps-assisted birth.

3. _______ is a genetic disorder in which blood does not clot properly.

Correct answer: B

Rationale: Hemophilia is a genetic disorder characterized by a deficiency in blood clotting factors, leading to prolonged bleeding. Cystic fibrosis is a genetic disorder that affects the lungs and digestive system, not blood clotting. Lymphoma is a type of cancer originating in the lymphatic system and is not related to blood clotting abnormalities. Huntington's disease is a neurodegenerative genetic disorder that affects a person's ability to move, think, and behave.

4. What is the structure of deoxyribonucleic acid (DNA)?

Correct answer: B

Rationale: The correct answer is B: double helix. DNA is structured as a double helix, resembling a twisted ladder made up of two strands of nucleotides. Choice A, single spiral, is incorrect as DNA is not a single spiral structure. Choice C, sphere, is incorrect as DNA does not form a spherical shape. Choice D, cube, is incorrect as DNA does not have a cubic structure. Understanding the double helix structure of DNA is essential as it allows for the storage and transmission of genetic information in living organisms.

5. According to a study in 2014 by Skakkebaek et al., who among the following is most likely to have gynecomastia?

Correct answer: C

Rationale: Individuals with Klinefelter syndrome have an extra X chromosome (XXY) and typically have reduced testosterone levels, which can lead to gynecomastia (enlarged breasts). This condition is not usually associated with Down syndrome (choice A), XYY syndrome (choice B), or Turner syndrome (choice D), making them less likely to have gynecomastia.

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