HESI LPN
HESI Maternal Newborn
1. Which drug was marketed in the 1960s to pregnant women and caused birth defects such as missing or stunted limbs in infants?
- A. Progestin
- B. Estrogen
- C. Thalidomide
- D. Oxytocin
Correct answer: C
Rationale: Thalidomide is the correct answer. Thalidomide was a drug marketed in the 1960s to pregnant women as a sedative and anti-nausea medication but tragically led to severe birth defects, including limb deformities, when taken during pregnancy. Progestin (Choice A) and Estrogen (Choice B) are hormones that are not associated with causing birth defects like Thalidomide. Oxytocin (Choice D) is a hormone that plays a role in labor and breastfeeding and is not known to cause birth defects like Thalidomide.
2. Following an amniocentesis, a nurse is caring for a client. The nurse should observe the client for which of the following complications?
- A. Hyperemesis
- B. Proteinuria
- C. Hypoxia
- D. Hemorrhage
Correct answer: D
Rationale: After an amniocentesis, the nurse should monitor the client for potential complications, with hemorrhage being a significant concern due to the invasive nature of the procedure. Hyperemesis (severe vomiting), proteinuria (excessive protein in the urine), and hypoxia (low oxygen levels) are not typically associated with amniocentesis and are less likely to occur compared to hemorrhage, which is a more common complication that requires prompt recognition and intervention.
3. What is the process in which the double helix of deoxyribonucleic acid (DNA) duplicates?
- A. Amniocentesis
- B. Mitosis
- C. Meiosis
- D. Mutation
Correct answer: B
Rationale: Mitosis is the correct answer because it is the process of cell division in which a cell duplicates its DNA and divides into two identical daughter cells. During mitosis, the DNA is replicated, and each daughter cell receives an identical copy of the genetic material. Amniocentesis is a medical procedure to collect amniotic fluid for prenatal genetic testing and is not related to DNA duplication. Meiosis is a type of cell division that produces gametes with half the genetic material of the parent cell, leading to genetic diversity. Mutation is a permanent alteration in the DNA sequence that can lead to genetic variations but is not the process of DNA duplication.
4. In the context of an average ejaculation, which of the following statements is true about sperm?
- A. The average count of sperm in the ejaculate is 2.5 billion.
- B. Sperm in the ejaculate find the ovum by following the current of the fluid coming from the cervix.
- C. Only 1 in 1,000 sperm in the ejaculate will ever approach an ovum.
- D. Most of the sperm in the ejaculate move about in a random pattern in the vagina.
Correct answer: C
Rationale: Out of millions of sperm released during ejaculation, only a small fraction, about 1 in 1,000, will approach the ovum. This statement is true as sperm face many obstacles and challenges on their journey to reach and fertilize an ovum. Choice A is incorrect because the average count of sperm in an ejaculate is typically in the millions, not billions. Choice B is incorrect as sperm do not find the ovum by following the current of fluid; they navigate using other mechanisms. Choice D is incorrect because while some sperm may move randomly in the vagina, the ones that approach the ovum do so through a more purposeful and directed movement.
5. A nurse is developing an educational program about hemolytic diseases in newborns for a group of newly licensed nurses. Which of the following genetic information should the nurse include in the program as a cause of hemolytic disease?
- A. The mother is Rh positive, and the father is Rh negative
- B. The mother is Rh negative, and the father is Rh positive
- C. The mother and the father are both Rh positive
- D. The mother and the father are both Rh negative
Correct answer: B
Rationale: The correct answer is B: 'The mother is Rh negative, and the father is Rh positive.' Hemolytic disease of the newborn occurs when an Rh-negative mother carries an Rh-positive fetus, leading to Rh incompatibility. In this scenario, the mother produces antibodies against the Rh antigen present in the fetus, which can result in hemolysis of the fetal red blood cells. Choices A, C, and D do not describe the Rh incompatibility that leads to hemolytic disease in newborns. Therefore, they are incorrect.
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