HESI LPN
Pharmacology HESI 2023
1. A client with severe depression is prescribed sertraline. Which statement by the client indicates the need for further teaching?
- A. I can stop taking this medication once I feel better.
- B. It may take 1 to 4 weeks to notice improvement in symptoms.
- C. I should avoid alcohol while taking this medication.
- D. I should take this medication in the morning with food.
Correct answer: A
Rationale: The correct answer is A. Clients should not stop taking sertraline abruptly once they feel better without consulting their healthcare provider. It is important to complete the full course of treatment as prescribed to prevent a relapse of symptoms. Stopping the medication suddenly can lead to withdrawal symptoms and may worsen the condition. Choice B is correct because sertraline may take 1 to 4 weeks to show noticeable improvement in symptoms. Choice C is correct as alcohol should be avoided while taking sertraline due to the increased risk of side effects. Choice D is also correct as taking sertraline in the morning with food can help reduce gastrointestinal side effects.
2. The client is receiving vancomycin, and the nurse plans to draw blood for a peak and trough to determine... the best timing for these levels?
- A. Midway through administration of the IV dose and 30 minutes before the next
- B. Two hours after completion of the IV dose and 30 minutes before the next
- C. Two hours after completion of the IV dose and one hour before the next
- D. Immediately after completion of the IV dose and 30 minutes before
Correct answer: B
Rationale: To accurately determine peak and trough levels of vancomycin, blood should be drawn two hours after the completion of the IV dose and 30 minutes before the next dose. This timing allows for appropriate assessment of the drug levels in the body, ensuring accurate monitoring of therapeutic and toxic concentrations. Choice A is incorrect as drawing blood midway through administration does not provide an accurate peak level. Choice C is incorrect as drawing blood one hour before the next dose does not represent the trough level. Choice D is incorrect because drawing blood immediately after completion of the IV dose does not allow enough time for the drug to reach peak levels.
3. During a home visit, a client with a history of angina reports frequent headaches. The client recently started a new prescription for diltiazem, a calcium channel blocker. What action should the nurse take?
- A. Explain the importance of obtaining a blood sample promptly to test for medication toxicity
- B. Consult with the healthcare provider regarding the necessity of an opioid analgesic for pain relief
- C. Recommend the client to discontinue the medication until contacting the healthcare provider
- D. Instruct the client on the use of acetaminophen every 4-6 hours as needed for headaches
Correct answer: D
Rationale: The correct action for the nurse to take is to instruct the client to use acetaminophen for headaches. Acetaminophen is a suitable and safer option for managing headaches associated with calcium channel blockers like diltiazem. It is essential to avoid medications that can interact negatively with diltiazem, such as opioid analgesics. Discontinuing the medication abruptly without consulting the healthcare provider is not recommended. Monitoring for medication toxicity through blood samples is not typically indicated for managing headaches in this scenario.
4. A client with a diagnosis of generalized anxiety disorder is prescribed venlafaxine. The nurse should instruct the client that this medication may have which potential side effect?
- A. Nausea
- B. Dry mouth
- C. Insomnia
- D. Headache
Correct answer: A
Rationale: The correct answer is A: Nausea. Venlafaxine, a medication used for generalized anxiety disorder, can commonly cause nausea as a side effect. It is essential for clients to be aware of this potential side effect and advised to take the medication with food if nausea occurs. Choices B, C, and D are incorrect because dry mouth, insomnia, and headache are less commonly associated side effects of venlafaxine compared to nausea.
5. When a client with hepatic encephalopathy is receiving lactulose, which parameter is essential to monitor for a response to the drug?
- A. Serum hepatic enzymes
- B. Fingerstick glucose
- C. Stool color and character
- D. Serum electrolytes and ammonia
Correct answer: D
Rationale: In hepatic encephalopathy, the goal of lactulose therapy is to reduce blood ammonia levels by promoting its excretion in the stool. Therefore, monitoring serum electrolytes and ammonia levels is crucial to assess the effectiveness of lactulose in lowering ammonia levels and improving the client's condition. Options A, B, and C are incorrect because serum hepatic enzymes, fingerstick glucose, and stool color/character are not directly related to monitoring the response to lactulose therapy in hepatic encephalopathy.
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