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HESI Maternal Newborn
1. Which of the following illnesses causes degeneration of the central nervous system?
- A. Tay-Sachs disease
- B. Cystic fibrosis
- C. Turner syndrome
- D. Klinefelter syndrome
Correct answer: A
Rationale: Tay-Sachs disease is a genetic disorder that causes a progressive degeneration of the central nervous system, particularly in infants. Choice B, Cystic fibrosis, is a genetic disorder that primarily affects the lungs and digestive system, not the central nervous system. Choices C and D, Turner syndrome and Klinefelter syndrome, are chromosomal disorders that do not directly involve degeneration of the central nervous system.
2. _____ are environmental agents that can harm the embryo or fetus.
- A. Mutations
- B. Autosomes
- C. Teratogens
- D. Androgens
Correct answer: C
Rationale: Teratogens are environmental agents, such as drugs, chemicals, or infections, that can cause harm to a developing embryo or fetus. Mutations (Choice A) refer to changes in the DNA sequence and are not environmental agents. Autosomes (Choice B) are chromosomes that are not involved in determining an individual's sex and are not environmental agents that harm the embryo or fetus. Androgens (Choice D) are a group of hormones that are more related to male sexual development and function, not environmental agents that harm the embryo or fetus.
3. After mitosis, the genetic code is identical in new cells unless _________ occur through radiation or other environmental influences.
- A. reductions
- B. expulsions
- C. conceptions
- D. mutations
Correct answer: D
Rationale: After mitosis, the genetic code is typically preserved and remains identical in the new cells. However, mutations can occur due to radiation or environmental influences, leading to changes in the DNA sequence and potentially altering the genetic code. Therefore, the correct answer is 'mutations.' Choices A, B, and C are incorrect because reductions, expulsions, and conceptions do not accurately describe the changes in the genetic code that can result from external factors. Mutations are the only option that reflects the alteration in the genetic code caused by external influences, making it the correct choice in this context.
4. Rubella, also called German measles, is a viral infection passed from the mother to the fetus that can cause birth defects such as deafness, intellectual disabilities, blindness, and heart disease in the embryo.
- A. Rubella
- B. Syphilis
- C. Cystic fibrosis
- D. Phenylketonuria
Correct answer: A
Rationale: Rubella, also known as German measles, is a viral infection that can lead to severe birth defects when contracted by a mother during pregnancy. Rubella is the correct answer because it is specifically associated with causing birth defects such as deafness, intellectual disabilities, blindness, and heart disease in the embryo. Syphilis (Choice B) can be passed from mother to fetus but does not cause the mentioned birth defects associated with Rubella. Cystic fibrosis (Choice C) and Phenylketonuria (Choice D) are genetic conditions and not infections transmitted from mother to fetus, making them incorrect choices in this context.
5. Rico is a man who has enlarged breasts and suffers from mild mental retardation. He has a problem learning languages, and his body produces less of the male sex hormone testosterone than normal males. Rico is most likely suffering from:
- A. Klinefelter syndrome.
- B. Tay-Sachs disease.
- C. Turner syndrome.
- D. Down syndrome.
Correct answer: A
Rationale: Rico's symptoms align with Klinefelter syndrome, which is characterized by an extra X chromosome in males (XXY). Enlarged breasts (gynecomastia), mild mental retardation, learning difficulties, and reduced testosterone production are common features of Klinefelter syndrome. Choice B, Tay-Sachs disease, is a genetic disorder that affects the nervous system and is not associated with the symptoms described. Choice C, Turner syndrome, occurs in females with a missing or partially missing X chromosome and does not fit Rico's profile. Choice D, Down syndrome, is caused by an extra copy of chromosome 21 and typically does not present with the symptoms mentioned for Rico.
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