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HESI Maternal Newborn
1. Which of the following illnesses causes degeneration of the central nervous system?
- A. Tay-Sachs disease
- B. Cystic fibrosis
- C. Turner syndrome
- D. Klinefelter syndrome
Correct answer: A
Rationale: Tay-Sachs disease is a genetic disorder that causes a progressive degeneration of the central nervous system, particularly in infants. Choice B, Cystic fibrosis, is a genetic disorder that primarily affects the lungs and digestive system, not the central nervous system. Choices C and D, Turner syndrome and Klinefelter syndrome, are chromosomal disorders that do not directly involve degeneration of the central nervous system.
2. What is the typical sex chromosome pattern for females?
- A. XX
- B. XYY
- C. XY
- D. XXY
Correct answer: A
Rationale: The typical sex chromosome pattern for females is XX. Females have two X chromosomes, which is represented as XX. Choice B (XYY) is incorrect as it represents the sex chromosome pattern for males with an extra Y chromosome. Choice C (XY) is the sex chromosome pattern for males. Choice D (XXY) represents a genetic disorder known as Klinefelter syndrome, where males have an extra X chromosome.
3. According to a study conducted in 2013 by Fellman, what affects the chances of having twins?
- A. Increase when a woman conceives at a younger age.
- B. Increase with parental age.
- C. Decrease with the frequency of intercourse before conception.
- D. Decrease with the use of fertility drugs.
Correct answer: B
Rationale: The correct answer is B. According to the study by Fellman in 2013, the chances of having twins actually increase with parental age. Choice A is incorrect as the study does not specify a younger age for conceiving to increase the chances of twins. Choice C is incorrect as the frequency of intercourse before conception is not a highlighted factor in the study. Choice D is also incorrect as the study does not discuss the impact of fertility drugs on the likelihood of having twins.
4. Twenty-year-old Jack is extremely tall and has very thick facial hair. Most of his male secondary sex characteristics are also more pronounced than men of his age. In this scenario, Jack is most likely:
- A. an XYY male.
- B. diagnosed with Klinefelter syndrome.
- C. an XXY male.
- D. diagnosed with Down syndrome.
Correct answer: A
Rationale: The correct answer is A: an XYY male. Individuals with XYY syndrome often exhibit increased height and more pronounced secondary male characteristics, such as thick facial hair. Choice B, Klinefelter syndrome (XXY), typically presents with less prominent male secondary sex characteristics due to the presence of an extra X chromosome. Choice C, XXY male, refers to Klinefelter syndrome, which does not align with the description of Jack having more pronounced male secondary sex characteristics. Choice D, Down syndrome, is caused by a trisomy of chromosome 21 and is not associated with the physical characteristics described in the scenario.
5. Which neonatal complications are associated with hypertension in the mother?
- A. Intrauterine growth restriction (IUGR) and prematurity.
- B. Seizures and cerebral hemorrhage.
- C. Hepatic or renal dysfunction.
- D. Placental abruption and DIC.
Correct answer: A
Rationale: Neonatal complications associated with maternal hypertension are primarily due to placental insufficiency. The correct answer is A, which includes Intrauterine Growth Restriction (IUGR) and prematurity. These complications arise from inadequate blood flow to the fetus, leading to growth restriction and premature birth. Choices B, seizures, and cerebral hemorrhage are more commonly maternal complications rather than neonatal ones. Choice C, hepatic or renal dysfunction, pertains to maternal complications of hypertensive disorders in pregnancy, not neonatal issues. Choice D, placental abruption, and Disseminated Intravascular Coagulation (DIC) are conditions linked to maternal morbidity and mortality, not neonatal complications.
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