what is the term for the study of how diet affects gene expression
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Nutrition Final Exam

1. What is the term for the study of how diet affects gene expression?

Correct answer: B

Rationale: Nutrigenomics is the study of how diet affects gene expression, influencing health outcomes and disease risk. Epigenetics (choice A) involves changes in gene expression or cellular phenotype caused by mechanisms other than changes in the underlying DNA sequence. Genomics (choice C) is the study of an organism's entire genome. Genetics (choice D) is the study of heredity and the variation of inherited characteristics.

2. What dietary recommendation is essential for a child with phenylketonuria (PKU)?

Correct answer: C

Rationale: The correct answer is C: 'Low-phenylalanine diet.' Children with phenylketonuria (PKU) need to follow a low-phenylalanine diet to manage the condition. Phenylalanine is an amino acid found in protein-containing foods, and individuals with PKU have difficulty metabolizing it, leading to neurological damage and other complications. Therefore, restricting phenylalanine intake is crucial. Choice A, 'High-protein diet,' is incorrect because high protein intake would increase phenylalanine levels, worsening the condition. Choice B, 'Low-fat diet,' and Choice D, 'High-fiber diet,' are not the primary focus for PKU patients. The key dietary intervention for PKU is controlling phenylalanine intake, which is best achieved through a low-phenylalanine diet.

3. What is the result of the metabolism of energy nutrients?

Correct answer: A

Rationale: The correct answer is A. Energy is released during the metabolism of energy nutrients. This released energy is utilized by the body for various functions. Choice B is incorrect because the metabolism of energy nutrients does not directly result in an increase in body fat. Choice C is incorrect as energy is not destroyed but rather transformed and utilized by the body. Choice D is incorrect as the metabolism of energy nutrients does not lead to a decrease in body water.

4. What is a causative factor of Hirschsprung disease?

Correct answer: C

Rationale: The correct answer is C: Absence of parasympathetic ganglion cells in a portion of the colon. Hirschsprung disease is a congenital condition characterized by the absence of nerve cells (ganglia) in parts of the colon. This absence leads to a lack of peristalsis in the affected segment, resulting in severe constipation and bowel obstruction. Choices A, B, and D are incorrect. Choice A describes symptoms of diarrhea rather than a causative factor of Hirschsprung disease. Excessive peristaltic movement (choice B) is not a causative factor but rather the opposite, as Hirschsprung disease is associated with reduced peristalsis. Choice D, which refers to intussusception, is a different condition unrelated to Hirschsprung disease.

5. What is the primary goal in managing a child with asthma?

Correct answer: B

Rationale: The primary goal in managing a child with asthma is to avoid triggering asthma attacks. This involves managing allergens, ensuring proper medication use, and creating an asthma action plan. Choice A is incorrect because the goal is to avoid triggering asthma attacks, not necessarily to prevent recurrent infections. Choice C is incorrect as corticosteroids are a treatment option but not the primary goal of asthma management. Choice D is incorrect because although physical activity is important, the primary goal is to prevent asthma attacks and manage symptoms effectively.

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