HESI LPN
HESI Practice Test Pharmacology
1. When planning to administer the antiulcer GI agent sucralfate, what instruction should the nurse provide regarding administration?
- A. Administer sucralfate once a day
- B. Assess for secondary candida infection
- C. Monitor electrolyte imbalance
- D. Give sucralfate on an empty stomach
Correct answer: D
Rationale: Sucralfate is most effective when taken on an empty stomach. This allows the medication to form a protective layer over the ulcer, promoting healing and symptom relief. Administering sucralfate with or after meals may reduce its efficacy as it may bind to food instead of coating the ulcer site.
2. A client has been diagnosed with open-angle glaucoma. The healthcare provider prescribes pilocarpine 1% eye drops. The nurse explains that which action of this drug makes it a useful treatment for the client's condition?
- A. The ciliary muscle contracts, increasing the outflow of aqueous humor in the eye.
- B. Ciliary muscles are paralyzed to decrease accommodation.
- C. Bilateral mydriasis with cycloplegia is accomplished.
- D. The production of aqueous humor in the eyes is decreased.
Correct answer: A
Rationale: Pilocarpine, a cholinergic agent, stimulates the ciliary muscle to contract, which opens the trabecular meshwork and facilitates the outflow of aqueous humor, reducing intraocular pressure. This mechanism helps in managing open-angle glaucoma by improving drainage and lowering pressure within the eye. Choice A is correct because the contraction of the ciliary muscle increases the outflow of aqueous humor, aiding in the treatment of open-angle glaucoma. Choices B, C, and D are incorrect because they do not describe the mechanism of action of pilocarpine in treating glaucoma.
3. A client with type 2 diabetes mellitus is prescribed exenatide. The nurse should monitor for which potential adverse effect?
- A. Nausea
- B. Hypoglycemia
- C. Hyperglycemia
- D. Pancreatitis
Correct answer: A
Rationale: Exenatide, a medication commonly used in type 2 diabetes, is known to cause gastrointestinal side effects, such as nausea. Monitoring for nausea is essential as it can lead to decreased appetite and potential weight loss, affecting the nutritional status of the client. While hypoglycemia and hyperglycemia are important to monitor in diabetes management, they are not typically associated with exenatide use. Pancreatitis is a rare but serious adverse effect of exenatide, which requires immediate medical attention if suspected.
4. A client with hypertension is prescribed doxazosin. The nurse should monitor for which potential side effect?
- A. Hypotension
- B. Hypertension
- C. Hyperglycemia
- D. Hypernatremia
Correct answer: A
Rationale: The correct answer is A: Hypotension. Doxazosin is an alpha-blocker medication commonly used to treat hypertension. One of the potential side effects of doxazosin is causing a sudden drop in blood pressure, leading to hypotension. Therefore, the nurse should closely monitor the client for signs and symptoms of low blood pressure when initiating or adjusting the dose of doxazosin.
5. A client with a diagnosis of generalized anxiety disorder is prescribed citalopram. The nurse should instruct the client that this medication may have which potential side effect?
- A. Nausea
- B. Drowsiness
- C. Insomnia
- D. Headache
Correct answer: A
Rationale: The correct potential side effect of citalopram is nausea. Citalopram can cause gastrointestinal disturbances such as nausea, so clients should be advised to take the medication with food if nausea occurs to help minimize this side effect. While other side effects like drowsiness, insomnia, and headache may also occur with citalopram, nausea is a common side effect that clients should be informed about. Drowsiness and insomnia are more commonly associated with other medications used to treat anxiety or depression, such as benzodiazepines or certain antidepressants. Headache is a less common side effect of citalopram compared to nausea.
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