HESI LPN
HESI Practice Test Pharmacology
1. Phenazopyridine is commonly prescribed for clients with urinary tract infections (UTI). Which statement by the practical nurse describes the purpose for the administration of phenazopyridine?
- A. To alter the pH level of the urine
- B. To reduce the frequency of bladder spasms
- C. To alleviate the painful symptoms caused by the UTI
- D. To prevent bacterial replication and resistance development
Correct answer: C
Rationale: The correct answer is C. Phenazopyridine, a urinary analgesic, is utilized to alleviate the pain associated with urinary tract infections (UTIs) like burning, pain, urgency, and frequent voiding. The administration of phenazopyridine can cause the urine to turn a bright red-orange color. It is recommended to take this medication with food to reduce gastric irritation. Phenazopyridine should only be used for a maximum of 2 days when taken alongside an antibacterial agent, which is typically prescribed for about 2 weeks to treat the underlying infection.
2. A client with a diagnosis of schizophrenia is prescribed olanzapine. The nurse should monitor for which potential side effect?
- A. Weight gain
- B. Insomnia
- C. Dry mouth
- D. Headache
Correct answer: A
Rationale: When a client with schizophrenia is prescribed olanzapine, the nurse should monitor for weight gain as a potential side effect. Olanzapine is known to cause metabolic changes that can lead to weight gain, making it crucial for the nurse to closely monitor the client's weight during treatment. This side effect is significant as it can impact the client's overall health and well-being, so early detection and intervention are essential to manage it effectively.
3. The nurse is preparing a client with chronic obstructive pulmonary disease, which medication should the nurse review with the client to manage this?
- A. Guaifenesin
- B. Prednisone
- C. Salmeterol
- D. Tiotropium
Correct answer: D
Rationale: Tiotropium is commonly used for COPD management.
4. A client who received a renal transplant three months ago is readmitted to the acute care unit with signs of graft rejection. While taking the client's history, the nurse determines the client has been self-administering St. John's wort, an herbal preparation, on the advice of a friend. What information is most significant about this finding?
- A. Wort can decrease plasma concentration of Cyclospora
- B. Wort can decrease plasma concentration of Tacrolimus
- C. Wort can decrease plasma concentration of Cyclosporine
- D. Wort can decrease plasma concentration of Mycophenolate
Correct answer: C
Rationale: The most significant information about the client self-administering St. John's wort, an herbal preparation, is that it can decrease the plasma concentration of Cyclosporine. St. John's wort is known to reduce the efficacy of Cyclosporine, which is a common immunosuppressant drug used to prevent transplant rejection. Choices A, B, and D are incorrect because St. John's wort does not affect the plasma concentration of Cyclospora, Tacrolimus, or Mycophenolate.
5. A client with chronic kidney disease is prescribed sevelamer. The nurse should monitor for which potential side effect?
- A. Hypercalcemia
- B. Hypocalcemia
- C. Hyperkalemia
- D. Hypokalemia
Correct answer: B
Rationale: When a client with chronic kidney disease is prescribed sevelamer, the nurse should monitor for hypocalcemia. Sevelamer works by binding dietary phosphorus in the gastrointestinal tract, which can lead to decreased calcium absorption and potentially cause hypocalcemia.
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