Nursing Elites

1. Individuals with Klinefelter syndrome produce:

• A. less estrogen than normal males.
• B. less testosterone than normal males.
• C. less adenine than normal males.
• D. less thymine than normal males.

Correct answer: B

Rationale: Individuals with Klinefelter syndrome have an extra X chromosome (XXY), leading to reduced production of testosterone, the primary male sex hormone. This deficiency can result in various physical and developmental characteristics associated with the syndrome. Estrogen levels may actually be relatively elevated due to the imbalance between testosterone and estrogen. Choices C and D are incorrect as adenine and thymine are nucleotide bases found in DNA and are not related to hormone production.

2. How many chromosomes are typically found in human cells, organized into pairs?

• A. 50
• B. 46
• C. 48
• D. 44

Correct answer: B

Rationale: Human cells typically contain 46 chromosomes organized into 23 pairs. This is the correct number for a normal human cell. Choices A, C, and D are incorrect because they do not represent the typical chromosome count in human cells.

3. Thalidomide was marketed in the 1960s as a treatment for:

• A. insomnia and nausea.
• B. infertility and impotence.
• C. Down syndrome.
• D. Turner syndrome.

Correct answer: A

Rationale: Thalidomide was initially marketed as a treatment for insomnia and nausea, particularly in pregnant women. However, it was later found to cause severe birth defects, leading to significant consequences. Choice B, infertility and impotence, is incorrect as thalidomide was not marketed for these conditions. Choices C and D, Down syndrome and Turner syndrome, are genetic conditions and not conditions for which thalidomide was intended as a treatment.

4. Which of the following most accurately describes the function of genes?

• A. They regulate the development of traits.
• B. They prevent foreign particles from entering the body.
• C. They work together with lutein to influence development.
• D. They transfer oxygen from the bloodstream to other parts of the body.

Correct answer: A

Rationale: The correct answer is A: 'They regulate the development of traits.' Genes play a crucial role in regulating the development of traits by encoding proteins that control various bodily functions and characteristics. This process involves gene expression and the production of proteins that ultimately determine an individual's traits. Choice B is incorrect because genes do not have a direct role in preventing foreign particles from entering the body; this function is primarily carried out by the immune system. Choice C is incorrect as genes do not specifically work with lutein to influence development; genes operate independently to regulate trait expression. Choice D is incorrect as genes are not responsible for transferring oxygen in the bloodstream; this function is carried out by red blood cells and hemoglobin.

5. Does the probability of having a child with Down’s syndrome increase with the age of the parents?

• A. TRUE
• B. FALSE
• C. Sometimes
• D. Never

Correct answer: A

Rationale: The correct answer is A: TRUE. Advanced parental age, particularly maternal age, is associated with an increased risk of Down's syndrome in offspring. As parents get older, the likelihood of having a child with Down's syndrome increases. Choices B, C, and D are incorrect because the risk of Down's syndrome is known to rise with parental age, especially maternal age, due to the increased likelihood of chromosomal abnormalities during egg formation.

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