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Pharmacology HESI 2023 Quizlet
1. A client with diabetes mellitus type 2 is prescribed pioglitazone. The nurse should monitor for which potential adverse effect?
- A. Weight gain
- B. Liver toxicity
- C. Kidney stones
- D. Bone fractures
Correct answer: B
Rationale: The correct answer is B, liver toxicity. Pioglitazone is known to cause liver toxicity, so it is essential for the nurse to monitor the client's liver function while on this medication. Monitoring liver function tests can help detect any signs of liver damage early, allowing for timely intervention to prevent serious complications.
2. The client is receiving vancomycin, and the nurse plans to draw blood for a peak and trough to determine... the best timing for these levels?
- A. Midway through administration of the IV dose and 30 minutes before the next
- B. Two hours after completion of the IV dose and 30 minutes before the next
- C. Two hours after completion of the IV dose and one hour before the next
- D. Immediately after completion of the IV dose and 30 minutes before
Correct answer: B
Rationale: To accurately determine peak and trough levels of vancomycin, blood should be drawn two hours after the completion of the IV dose and 30 minutes before the next dose. This timing allows for appropriate assessment of the drug levels in the body, ensuring accurate monitoring of therapeutic and toxic concentrations. Choice A is incorrect as drawing blood midway through administration does not provide an accurate peak level. Choice C is incorrect as drawing blood one hour before the next dose does not represent the trough level. Choice D is incorrect because drawing blood immediately after completion of the IV dose does not allow enough time for the drug to reach peak levels.
3. What instruction should the nurse include in the teaching plan for a client prescribed etanercept for rheumatoid arthritis?
- A. Rotate injection sites to prevent irritation.
- B. Take this medication with food to reduce gastrointestinal upset.
- C. Avoid sunlight exposure while on this medication.
- D. Notify the healthcare provider of any signs of infection.
Correct answer: A
Rationale: The correct instruction for a client prescribed etanercept is to rotate injection sites to prevent irritation and ensure proper absorption. Changing sites will help prevent skin irritation and ensure that the medication is absorbed effectively. This practice also reduces the risk of injection site reactions and discomfort. It is essential to follow this instruction to promote optimal medication delivery and minimize adverse effects. Choice B is incorrect because etanercept can be taken with or without food, and it is not specifically indicated to be taken with food to reduce gastrointestinal upset. Choice C is incorrect as there is no specific association between etanercept and sunlight exposure. Choice D is incorrect because while it is important to notify the healthcare provider of signs of infection, this is not the primary instruction related to the administration of etanercept.
4. How should the healthcare provider schedule the administering of propylthiouracil (PTU)?
- A. Offer both drugs together with a meal
- B. Give parental dose once every 24 hours
- C. Schedule both medications at bedtime
- D. Administer iodine one hour before PTU
Correct answer: D
Rationale: Administering iodine one hour before PTU is crucial to ensure proper absorption and effectiveness of PTU. This timing helps optimize the therapeutic benefits of PTU by allowing it to be absorbed efficiently without interference from iodine, ultimately leading to better treatment outcomes for the patient. Choices A, B, and C are incorrect because offering both drugs together with a meal, giving parental dose once every 24 hours, and scheduling both medications at bedtime do not address the specific timing requirement of administering iodine before PTU for optimal absorption.
5. A client with a diagnosis of bipolar disorder is prescribed lithium. The nurse should monitor for which potential side effect?
- A. Dry mouth
- B. Hair loss
- C. Weight gain
- D. Tremors
Correct answer: D
Rationale: The correct answer is D: Tremors. When a client is prescribed lithium for bipolar disorder, one common side effect to monitor for is tremors. Tremors are a known adverse effect of lithium therapy and should be monitored closely by healthcare providers. Choice A, dry mouth, is not typically associated with lithium use. Hair loss, as in choice B, is not a common side effect of lithium. Weight gain, as mentioned in choice C, can occur with some medications used to treat bipolar disorder, but it is not a prominent side effect of lithium specifically.
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