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Pharmacology HESI Practice
1. A client with diabetes mellitus type 2 is prescribed empagliflozin. The nurse should monitor for which potential adverse effect?
- A. Genital infections
- B. Hypoglycemia
- C. Hyperglycemia
- D. Nausea
Correct answer: A
Rationale: The correct answer is A: Genital infections. Empagliflozin, a medication commonly used to treat type 2 diabetes, is associated with an increased risk of genital infections. This is due to its mechanism of action, which involves promoting the excretion of glucose through urine, creating a more favorable environment for fungal or bacterial growth in the genital area. Choices B and C, hypoglycemia and hyperglycemia, are less likely adverse effects of empagliflozin. Empagliflozin actually carries a low risk of causing hypoglycemia since it works independently of insulin. Nausea (Choice D) is not a commonly reported adverse effect of empagliflozin, making it an incorrect choice in this scenario.
2. A client with rheumatoid arthritis is prescribed tofacitinib. What should the nurse include in the client's teaching plan?
- A. Avoid live vaccines while taking this medication.
- B. Take this medication with food to decrease gastrointestinal upset.
- C. Report any signs of infection to the healthcare provider.
- D. Avoid sunlight while taking this medication.
Correct answer: A
Rationale: Tofacitinib is an immunosuppressive medication used in rheumatoid arthritis. Patients taking tofacitinib should avoid live vaccines because the medication can weaken the immune system, making live vaccines potentially harmful. It is essential to educate the client on this to prevent any complications related to live vaccines during their treatment.
3. Phenytoin is prescribed for a client who has a seizure disorder. Which statement by the client needs to be clarified by the healthcare provider?
- A. I should notify the healthcare provider if the color of my urine turns pink.
- B. I should never stop taking this medication abruptly.
- C. I should monitor my glucose levels closely since I am diabetic.
- D. I should take the medicine with antacids if gastric upset occurs.
Correct answer: D
Rationale: The correct answer is D because antacids should not be taken with phenytoin as they can decrease its effects. Taking antacids with phenytoin is not recommended. Choice A is correct; pink discoloration of urine can occur with phenytoin use. Choice B is also correct; abruptly stopping phenytoin can lead to seizures. Choice C is correct; monitoring glucose levels is important as phenytoin can increase glucose levels. Therefore, the statement about using antacids with phenytoin needs clarification.
4. A client diagnosed with multiple sclerosis self-administers beta-1 interferon subcutaneously
- A. Explain to the client that the medication dose may need to be increased
- B. Instruct the client to withhold the drug until the next exacerbation
- C. Advise the client to consult the healthcare provider as soon as possible
- D. Encourage the client to continue taking the medication
Correct answer: D
Rationale: Encouraging the client to continue taking the medication is crucial in the management of multiple sclerosis. Beta-1 interferon is a disease-modifying drug used to reduce the frequency and severity of relapses in multiple sclerosis. Discontinuing the medication without medical advice can lead to disease exacerbation. It is essential for the client to maintain regular dosing to achieve optimal therapeutic effects and disease control.
5. A client with a diagnosis of schizophrenia is prescribed aripiprazole. The nurse should monitor the client for which potential side effect?
- A. Weight gain
- B. Dry mouth
- C. Headache
- D. Increased appetite
Correct answer: A
Rationale: Aripiprazole is known to cause weight gain in patients, so monitoring for changes in weight is essential to assess for this potential side effect and intervene accordingly.
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